ReviewBiotechnology for biofuels2018
Advances in metabolic modeling of oleaginous microalgae.
Review in Biotechnology for biofuels, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 83 citations in OpenAlex.
- Process intensification for the protein production from microalgae: a comprehensive review.Bioresources and bioprocessing · 2026Review
- Discovery of mannose as an alternative non-nutrient-deficient regulator of lipid accumulation in microalgae.Journal of advanced research · 2026Article
- Harnessing microalgae for bioproducts: innovations in synthetic biology.World journal of microbiology & biotechnology · 2025Review
- Constraint-based metabolic modeling reveals metabolic properties underpinning the unprecedented growth of Chlorella ohadii.The New phytologist · 2025Article
- Coarse-Grained Modeling Elucidates Differential Metabolism ofACS synthetic biology · 2025Article
- Algae and Cyanobacteria Fatty Acids and Bioactive Metabolites: Natural Antifungal Alternative AgainstMicroorganisms · 2025Review
- A Guide to Metabolic Network Modeling for Plant Biology.Plants (Basel, Switzerland) · 2025Review
- Natural color biofactories: advancing the spectrum of pigment production in phototrophic microbes.FEMS microbes · 2025Review
- Central transcriptional regulator controls photosynthetic growth and carbon storage in response to high light.Nature communications · 2024Article
- Proteomics and constraint-based modelling reveal enzyme kinetic properties of Chlamydomonas reinhardtii on a genome scale.Nature communications · 2023Article
- Metabolic network reconstruction ofFrontiers in microbiology · 2023Review
- Predicting stress response and improved protein overproduction in Bacillus subtilis.NPJ systems biology and applications · 2022Article
- The paradoxes hidden behind the Droop model highlighted by a metabolic approach.Frontiers in plant science · 2022Article
- Review
- Current perspectives on integrated approaches to enhance lipid accumulation in microalgae.3 Biotech · 2021Review
- MetaNetX/MNXref: unified namespace for metabolites and biochemical reactions in the context of metabolic models.Nucleic acids research · 2021Article
- Linking metabolic phenotypes to pathogenic traits among "Candidatus Liberibacter asiaticus" and its hosts.NPJ systems biology and applications · 2020Article
- Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth.Nature communications · 2020Article
- Dynamic resource allocation drives growth under nitrogen starvation in eukaryotes.NPJ systems biology and applications · 2020Article
- Current status and applications of genome-scale metabolic models.Genome biology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Production of biofuels and bioenergy precursors by phototrophic microorganisms, such as microalgae and cyanobacteria, is a promising alternative to conventional fuels obtained from non-renewable resources. Several species of microalgae have been investigated as potential candidates for the production of biofuels, for the most part due to their exceptional metabolic capability to accumulate large quantities of lipids. Constraint-based modeling, a systems biology approach that accurately predicts the metabolic phenotype of phototrophs, has been deployed to identify suitable culture conditions as well as to explore genetic enhancement strategies for bioproduction. Core metabolic models were employed to gain insight into the central carbon metabolism in photosynthetic microorganisms. More recently, comprehensive genome-scale models, including organelle-specific information at high resolution, have been developed to gain new insight into the metabolism of phototrophic cell factories. Here, we review the current state of the art of constraint-based modeling and computational method development and discuss how advanced models led to increased prediction accuracy and thus improved lipid production in microalgae.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.