ReviewJournal of occupational medicine and toxicology (London, England)2018
Olfactory dysfunction revisited: a reappraisal of work-related olfactory dysfunction caused by chemicals.
Review in Journal of occupational medicine and toxicology (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Pooled it
- Olfactory dysfunction among gas station employees exposed to fuel vapors using digital odor identification testing.iScience · 2026Article
- Formulation considerations in enhancing olfactory mucosal deposition for nose-to-brain drug delivery.Drug delivery and translational research · 2026Review
- Nasal Mucosal Heavy Metal Accumulation, Olfactory Dysfunction, and Histopathological Changes: A Prospective Clinical Study.Journal of clinical medicine · 2026Article
- Choroid plexus modulates subventricular zone adult neurogenesis and olfaction through secretion of small extracellular vesicles.Fluids and barriers of the CNS · 2026Article
- Comprehensive profiling of metal compound toxicity: potential novel targets and mechanistic insights using Tox21 screening.Journal of hazardous materials advances · 2026Article
- Choroid Plexus Modulates Subventricular Zone Adult Neurogenesis and Olfaction Through Secretion of Small Extracellular Vesicles.Research square · 2025Article
- Olfactory Nerve Transection Transiently Activates Olfactory Ensheathing Cells in Xenopus laevis Larvae.The European journal of neuroscience · 2025Article
- Impact of Manganese on Neuronal Function: An Exploratory Multi-Omics Study on Ferroalloy Workers in Brescia, Italy.Brain sciences · 2025Article
- Factors associated with loss and recovery of smell and taste after COVID-19 infection.Laryngoscope investigative otolaryngology · 2024Article
- A multi-environmental source approach to explore associations between metals exposure and olfactory identification among school-age children residing in northern Italy.Journal of exposure science & environmental epidemiology · 2024Article
- Zonisamide Ameliorated the Apoptosis and Inflammation in Cerebellar Tissue of Induced Alcohol Addiction Animal Model.Life (Basel, Switzerland) · 2024Article
- Platelet-Rich Plasma (PRP) in the Treatment of Long COVID Olfactory Disorders: A Comprehensive Review.Biomedicines · 2024Review
- Characterization of pathological changes in the olfactory system of mice exposed to methylmercury.Archives of toxicology · 2024Article
- Correlations between gustatory, trigeminal, and olfactory functions and nasal airflow.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- Assessment of COVID-19-related olfactory dysfunction and its association with psychological, neuropsychiatric, and cognitive symptoms.Frontiers in neuroscience · 2023Review
- Inaccurate self-report of olfactory dysfunction in REM Sleep Behaviour Disorder and implications for prognosis.Clinical parkinsonism & related disorders · 2023Article
- Neuropsychological symptoms in workers handling cargo from shipping containers and export logs.International archives of occupational and environmental health · 2022Review
- International consensus statement on allergy and rhinology: Olfaction.International forum of allergy & rhinology · 2022Review
- Perioperative Anesthesia and Acute Smell Alterations in Spine Surgery: A "Sniffing Impairment" Influencing Refeeding?Frontiers in surgery · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Occupational exposure to numerous individual chemicals has been associated with olfactory dysfunction, mainly in individual case descriptions. Comprehensive epidemiological investigations into the olfactotoxic effect of working substances show that the human sense of smell may be impaired by exposure to metal compounds involving cadmium, chromium and nickel, and to formaldehyde. This conclusion is supported by the results of animal experiments. The level of evidence for a relationship between olfactory dysfunction and workplace exposure to other substances is relatively weak.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.