ArticleImmunity & ageing : I & A2018
The baseline levels and risk factors for high-sensitive C-reactive protein in Chinese healthy population.
Article in Immunity & ageing : I & A, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 56 citations in OpenAlex.
- DELTA: Strengthening human biological resilience with an N=1 digital health and dynamic biomarker protocol.PloS one · 2026Trial
- Interindividual Variation in Chronic Inflammation in Northern Lao People's Democratic Republic.American journal of biological anthropology · 2026Article
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- Longitudinal assessment of inflammatory biomarkers among youth with perinatal HIV infection and HIV exposure.AIDS (London, England) · 2026Article
- Vascular age vs. chronological age in operative risk stratification.Frontiers in cardiovascular medicine · 2026Review
- Review
- Article
- Relating Biopsychosocial Meanings to Semi-Quantitative CRP Readings Among Primary Healthcare Users: Trends from a Cross-Sectional Study Analysis.Journal of clinical medicine · 2025Article
- Altered Anthropometrics and HbA1c Levels, but not Dyslipidemia, Are Associated With Elevated hs-CRP Levels in Middle-aged Adults: A Population-based Analysis.Critical pathways in cardiology · 2025Article
- A novel framework to build saliva-based DNA methylation biomarkers: Quantifying systemic chronic inflammation as a case study.Aging cell · 2025Article
- C-reactive Protein (CRP) in Patients With Myocarditis: A Systematic Review and Meta-Analysis.Cureus · 2024Review
- Higher Dietary Polyphenol Intake Is Associated With Lower Blood Inflammatory Markers.The Journal of nutrition · 2024Article
- Myocardial Perfusion Imaging and C-Reactive Protein in Myocardial Ischemia: A Retrospective Single-Center Study.Life (Basel, Switzerland) · 2024Article
- A biomarker framework for liver aging: the Aging Biomarker Consortium consensus statement.Life medicine · 2024Article
- Adherence to the American Cancer Society guidelines on nutrition and physical activity for cancer survivors and biomarkers of inflammation among breast cancer survivors.Epidemiology and health · 2024Article
- Construct Validation of the Dietary Inflammatory Index (DII) among Young College-Aged Women.Nutrients · 2023Article
- The Potential Role of C-Reactive Protein in Metabolic-Dysfunction-Associated Fatty Liver Disease and Aging.Biomedicines · 2023Review
- C-reactive protein levels and depression in older and younger adults - A study of 19,947 individuals. The Tromsø study.Brain, behavior, & immunity - health · 2023Article
- Blood inflammatory markers and mortality in the US population: A Health and Retirement Survey (HRS) analysis.PloS one · 2023Article
- Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent studies show that C-reactive protein (CRP) is not only a biomarker but also a pathogenic mediator contributing to the development of inflammation and ageing-related diseases. However, serum levels of CRP in the healthy ageing population remained unclear, which was investigated in the present study.
methodsSerum levels of high sensitive C-reactive protein (hs-CRP), glucose (Glu), triglyceride (TG), cholesterol (CHOL), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), superoxide dismutase (SOD), serum creatinine (SCr), serum uric acid (SUA) were measured in 6060healthy subjects (3672 male and 2388 female, mean age:45.9 years) who received routine physical examination at Sun Yat-sen Memorial Hospital, Guangzhou, China.
resultsIn total of 6060 healthy people, serum levels of hs-CRP were significantly increased with ageing (
conclusionsBaseline levels of serum hs-CRP are increased with ageing and are significantly higher in male than female healthy population. In addition, elevated serum levels of hs-CRP are also associated with increased SUA but decreased HDL-c and SOD. Thus, serum levels of hs-CRP may be an indicator associated with ageing in healthy Chinese population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.