ArticleNature chemistry2018
Stereoselective synthesis of a composite knot with nine crossings.
Article in Nature chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 145 citations in OpenAlex.
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- Discovery of an Interlocked and Interwoven Molecular Topology in Nanocarbons via Dynamic C-C Bond Formation.Journal of the American Chemical Society · 2025Article
- Characterizing X-Ray and Solution State Conformations for a Model Qubit System: {CrInorganic chemistry · 2024Article
- Phosphorescent metallaknots of Au(I)-bis(acetylide) strands directed by Cu(I) π-coordination.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Folding a Molecular Strand into a Trefoil Knot of Single Handedness with Co(II)/Co(III) Chaperones.Journal of the American Chemical Society · 2024Article
- A Coordination-Driven Self-Assembly and NIR Photothermal Conversion Study of Organometallic Handcuffs.Molecules (Basel, Switzerland) · 2023Article
- Dimeric and trimeric catenation of giant chiral [8 + 12] imine cubes driven by weak supramolecular interactions.Nature chemistry · 2023Article
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- Knotting matters: orderly molecular entanglements.Chemical Society reviews · 2022Review
- Highly selective synthesis and near-infrared photothermal conversion of metalla-Borromean ring and [2]catenane assemblies.Chemical science · 2022Article
- Distinctive features and challenges in catenane chemistry.Chemical science · 2022Review
- Molecular weaving.Nature materials · 2022Review
- Nonaqueous Emulsion Polycondensation Enabled by a Self-Assembled Cage-like Surfactant.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Symmetric tangled Platonic polyhedra.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- A molecular endless (7Nature chemistry · 2021Article
- Effects of turn-structure on folding and entanglement in artificial molecular overhand knots.Chemical science · 2020Article
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- Transmembrane Ion Channels Formed by a Star of David [2]Catenane and a Molecular Pentafoil Knot.Journal of the American Chemical Society · 2020Article
- The Role of Zinc(II) Ion in Fluorescence Tuning of Tridentate Pincers: A Review.Molecules (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The simultaneous synthesis of a molecular nine-crossing composite knot that contains three trefoil tangles of the same handedness and a [Formula: see text] link (a type of cyclic [3]catenane topologically constrained to always have at least three twists within the links) is reported. Both compounds contain high degrees of topological writhe (w = 9), a structural feature of supercoiled DNA. The entwined products are generated from the cyclization of a hexameric Fe(II) circular helicate by ring-closing olefin metathesis, with the mixture of topological isomers formed as a result of different ligand connectivity patterns. The metal-coordinated composite knot was isolated by crystallization, the topology unambiguously proven by tandem mass spectrometry, with X-ray crystallography confirming that the 324-atom loop crosses itself nine times with matching handedness (all Δ or all Λ) at every metal centre within each molecule. Controlling the connectivity of the ligand end groups on circular metal helicate scaffolds provides an effective synthetic strategy for the stereoselective synthesis of composite knots and other complex molecular topologies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.