Evidence map›Paper›PMID 30202089›Full record

ArticleNature2018

Experimental and computational framework for a dynamic protein atlas of human cell division.

Yin Cai, M Julius Hossain, Jean-Karim Hériché, Antonio Z Politi, Nike Walther, Birgit Koch, Malte Wachsmuth, Bianca Nijmeijer, Moritz Kueblbeck, Marina Martinic-Kavur and 4 more

Open access · greenAbstract read
In one paragraph

Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
20.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 132 citations in OpenAlex.

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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 4 countries.

Yin CaiEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
M Julius HossainEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Jean-Karim HérichéEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Antonio Z PolitiEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Nike WaltherEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Birgit KochEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Malte WachsmuthEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Bianca NijmeijerEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Moritz KueblbeckEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Marina Martinic-KavurResearch Institute of Molecular Pathology (IMP), Vienna, Austria.
Rene LadurnerResearch Institute of Molecular Pathology (IMP), Vienna, Austria.
Stephanie AlexanderEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Jan-Michael PetersResearch Institute of Molecular Pathology (IMP), Vienna, Austria.
Jan EllenbergEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany. jan.ellenberg@embl.de.
European Molecular Biology Laboratory · DEGenos (Croatia) · HRMax Planck Institute for Biophysical Chemistry · DEMax Planck Institute for Medical Research · DEResearch Institute of Molecular Pathology · ATRoche Pharma AG (Germany) · DEStanford Medicine · US

Funding

Reconstructing the dynamic 3D architecture of the human genome by superresolution microscopy and DNA sequence modelling.U01EB021223 · NIBIB · EUROPEAN MOLECULAR BIOLOGY LABORATORY · PI ELLENBERG, JAN · 2015 to 2017
$1.2M
Reconstructing the dynamic 3D architecture of the human genome by superresolution microscopy and DNA sequence modelling.U01DA047728 · NIDA · EUROPEAN MOLECULAR BIOLOGY LABORATORY · PI ELLENBERG, JAN · 2018 to 2019
$780k
NIBIB NIH HHS U01 EB021223NIDA NIH HHS U01 DA047728
6 · The paper itself

Abstract

Essential biological functions, such as mitosis, require tight coordination of hundreds of proteins in space and time. Localization, the timing of interactions and changes in cellular structure are all crucial to ensure the correct assembly, function and regulation of protein complexes

Indexed as

MitosisCell Cycle ProteinsGene EditingGreen Fluorescent ProteinsHeLa CellsHumansImaging, Three-DimensionalMicroscopy, FluorescenceMolecular ImagingTime FactorsCell Cycle Proteinsenhanced green fluorescent proteinGreen Fluorescent Proteins

Identifiers

PMID30202089
PMCPMC6556381
OpenAlexW2890313592

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.