Evidence map›Paper›PMID 30202022›Full record

ArticleScientific reports2018

Characterisation of pathogen-specific regions and novel effector candidates in Fusarium oxysporum f. sp. cepae.

Andrew D Armitage, Andrew Taylor, Maria K Sobczyk, Laura Baxter, Bethany P J Greenfield, Helen J Bates, Fiona Wilson, Alison C Jackson, Sascha Ott, Richard J Harrison and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 121 citations in OpenAlex.

  1. Review
  2. Article
  3. Pathogenicity and Pre-Characterised Putative Effectors ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Fusarium Genome Sequencing and Assembly.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  9. Pathogenicity Differentiation ofPathogens (Basel, Switzerland) · 2024
    Article
  10. Article
  11. FoPGDB: a pangenome database of Fusarium oxysporum, a cross-kingdom fungal pathogen.Database : the journal of biological databases and curation · 2024
    Article
  12. OnionPlants (Basel, Switzerland) · 2024
    Article
  13. Review
  14. Pangenomics of flax fungal parasiteFrontiers in plant science · 2024
    Article
  15. Article
  16. The SIX5 Protein inMicroorganisms · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Andrew D ArmitageNIAB-EMR, New Road, East Malling, Kent, ME19 6BJ, UK.
Andrew TaylorWarwick Crop Centre, School of Life Sciences, University of Warwick, Wellesbourne, Warwick, CV35 9EF, UK.
Maria K SobczykNIAB-EMR, New Road, East Malling, Kent, ME19 6BJ, UK.
Laura BaxterWarwick Crop Centre, School of Life Sciences, University of Warwick, Wellesbourne, Warwick, CV35 9EF, UK.ORCID 0000-0003-3287-7547
Bethany P J GreenfieldNIAB-EMR, New Road, East Malling, Kent, ME19 6BJ, UK.
Helen J BatesNIAB-EMR, New Road, East Malling, Kent, ME19 6BJ, UK.
Fiona WilsonNIAB-EMR, New Road, East Malling, Kent, ME19 6BJ, UK.
Alison C JacksonWarwick Crop Centre, School of Life Sciences, University of Warwick, Wellesbourne, Warwick, CV35 9EF, UK.
Sascha OttDepartment of Computer Science, University of Warwick, CV4 7AL, Warwick, UK.
Richard J HarrisonNIAB-EMR, New Road, East Malling, Kent, ME19 6BJ, UK. richard.harrison@emr.ac.uk.ORCID 0000-0002-3307-3519
John P ClarksonWarwick Crop Centre, School of Life Sciences, University of Warwick, Wellesbourne, Warwick, CV35 9EF, UK.
East Malling Research (United Kingdom) · GBUniversity of Warwick · GB

Funding

Biotechnology and Biological Sciences Research Council (BBSRC) BB/K020730/1Biotechnology and Biological Sciences Research Council (BBSRC) BB/K020870/1Biotechnology and Biological Sciences Research Council (BBSRC) BB/K020870a/1
6 · The paper itself

Abstract

A reference-quality assembly of Fusarium oxysporum f. sp. cepae (Foc), the causative agent of onion basal rot has been generated along with genomes of additional pathogenic and non-pathogenic isolates of onion. Phylogenetic analysis confirmed a single origin of the Foc pathogenic lineage. Genome alignments with other F. oxysporum ff. spp. and non pathogens revealed high levels of syntenic conservation of core chromosomes but little synteny between lineage specific (LS) chromosomes. Four LS contigs in Foc totaling 3.9 Mb were designated as pathogen-specific (PS). A two-fold increase in segmental duplication events was observed between LS regions of the genome compared to within core regions or from LS regions to the core. RNA-seq expression studies identified candidate effectors expressed in planta, consisting of both known effector homologs and novel candidates. FTF1 and a subset of other transcription factors implicated in regulation of effector expression were found to be expressed in planta.

Indexed as

Chromosomes, FungalCrop ProductionFungal ProteinsFusariumGene Expression Regulation, FungalGenome, FungalMolecular Sequence AnnotationOnionsPhylogenyPlant DiseasesPlant RootsSequence Analysis, DNASyntenyTranscription FactorsVirulenceFtf1 protein, Fusarium oxysporumFungal ProteinsTranscription Factors

Identifiers

PMID30202022
PMCPMC6131394
OpenAlexW2890887245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.