ArticlePediatric research2018
Cerebral autoregulation and activity after propofol for endotracheal intubation in preterm neonates.
Article in Pediatric research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Cerebrovascular autoregulation and preterm brain injury: a systematic review and meta-analysis.Pediatric research · 2025Pooled it
- Cerebral Autoregulation in Non-Brain Injured Patients: A Systematic Review.Frontiers in neurology · 2021Pooled it
- Propofol use in newborns and children: is it safe? A systematic review.Jornal de pediatriaPooled it
- Propofol for endotracheal intubation in neonates: a dose-finding trial.Archives of disease in childhood. Fetal and neonatal edition · 2020Trial
- Neonatal sleep physiology and early executive functioning in preterm children.Pediatric research · 2026Article
- Monitoring of cerebral autoregulation during major surgery in adults, including cardiac surgery: mechanisms, anesthetic impacts, and clinical applications.Frontiers in medicine · 2026Review
- Pharmacological therapy of neonatal analgosedation: current status, dilemmas, and perspectives.Frontiers in pediatrics · 2026Review
- Dexmedetomidine for Less Invasive Surfactant Administration: Another Promising Medicine in an Ever-Growing Toolbox?Paediatric drugs · 2025Article
- Depression of cortical neuronal activity after a low-dose fentanyl in preterm infants.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Cerebral autoregulation in pediatric and neonatal intensive care: A scoping review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024Article
- Near-infrared spectroscopy monitoring of neonatal cerebrovascular reactivity: where are we now?Pediatric research · 2024Review
- Enhanced INSURE (ENSURE): an updated and standardised reference for surfactant administration.European journal of pediatrics · 2022Review
- Premedication before laryngoscopy in neonates: Evidence-based statement from the French society of neonatology (SFN).Frontiers in pediatrics · 2022Review
- Premedication with ketamine or propofol for less invasive surfactant administration (LISA): observational study in the delivery room.European journal of pediatrics · 2021Observational
- Propofol in neonates causes a dose-dependent profound and protracted decrease in blood pressure.Acta paediatrica (Oslo, Norway : 1992) · 2020Article
- Cerebrovascular Autoregulation in Preterm Infants During and After Surgical Ligation of the Ductus Arteriosus, a Comparison Between Two Surgical Approaches.Frontiers in pediatrics · 2020Article
- Cerebral Oxygenation During Neonatal Intubation-Ancillary Study of the Prettineo-Study.Frontiers in pediatrics · 2019Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite increasing use of propofol in neonates, observations on cerebral effects are limited.
aimTo investigate cerebral autoregulation (CAR) and activity after propofol for endotracheal intubation in preterm neonates.
methodsTwenty-two neonates received propofol before intubation as part of a published dose-finding study. Mean arterial blood pressure (MABP), near-infrared spectroscopy-derived cerebral oxygenation (rScO
resultsAfter intubation with a median propofol dose of 1 (0.5-4.5) mg/kg, rScO
conclusionsDrug-related hypotension and decreased cerebral activity after intubation with low propofol doses in preterm neonates were observed, without evidence of cerebral ischemic hypoxia. CAR remained intact during drug-related hypotension in 95.5% of patients. Cerebral monitoring including CAR clarifies the cerebral impact of MABP fluctuations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.