ArticleMolecules (Basel, Switzerland)2018
Quality Evaluation of Phellodendri Chinensis Cortex by Fingerprint⁻Chemical Pattern Recognition.
Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- ZishenWan reduces obesity inJournal of traditional and complementary medicine · 2026Article
- The Hepatoprotective Properties of the Revised Formulation of Dahuang Xiaoshi Tang, an Ancient Chinese Herbal Decoction, Are Probed by Integrated Metabolomics and Network Pharmacology.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Classification and Authentication of Lonicerae Japonicae Flos and Lonicerae Flos by UsingMolecules (Basel, Switzerland) · 2023Article
- Application of HPLC Fingerprint Combined with Chemical Pattern Recognition and Multi-Component Determination in Quality Evaluation ofMolecules (Basel, Switzerland) · 2022Article
- Qualitative and quantitative evaluationJournal of pharmaceutical analysis · 2022Article
- Chemical Antioxidant Quality Markers ofFrontiers in pharmacology · 2022Article
- Application of UHPLC Fingerprints Combined with Chemical Pattern Recognition Analysis in the Differentiation of SixMolecules (Basel, Switzerland) · 2021Article
- Application of fingerprint combined with quantitative analysis and multivariate chemometric methods in quality evaluation of dandelion (Royal Society open science · 2021Article
- Herbal nutraceutical treatment of chronic prostatitis-chronic pelvic pain syndrome: a literature review.International urology and nephrology · 2021Review
- Chemical Pattern Recognition for Quality Analysis of Lonicerae Japonicae Flos and Lonicerae Flos Based on Ultra-High Performance Liquid Chromatography and Anti-SARS-CoV2 Main Protease Activity.Frontiers in pharmacology · 2021Article
- Chemometric Analyses for the Characterization of Raw and Stir-Frying Processed Drynariae Rhizoma Based on HPLC Fingerprints.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Quality Evaluation ofMolecules (Basel, Switzerland) · 2019Article
- A strategy for qualitative and quantitative profiling of glycyrrhiza extract and discovery of potential markers by fingerprint-activity relationship modeling.Scientific reports · 2019Article
- Phellodendri Cortex: A Phytochemical, Pharmacological, and Pharmacokinetic Review.Evidence-based complementary and alternative medicine : eCAM · 2019Review
- Plant-Derived Alkaloids: The Promising Disease-Modifying Agents for Inflammatory Bowel Disease.Frontiers in pharmacology · 2019Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Phellodendri Chinensis Cortex (PCC) and Phellodendri Amurensis Cortex (PAC) are increasingly being used as traditional herbal medicines, but they are often mistaken for each other. In this study, the fingerprints of PCC from six different geographical sources were obtained by high-performance liquid chromatography, and multivariate chemometric methods were used for comprehensive analysis. Two unsupervised pattern recognition models (principal component analysis and hierarchical cluster analysis) and a supervised pattern recognition model (partial least squares discriminant analysis) were established on the basis of the chemical composition and physical traits of PCC and PAC. PCC and PAC were found to be distinguishable by these methods. The PCC category was divisible into two categories, one with more crude cork and a maximum thickness of ~1.5 mm, and the other with less net crude cork and a maximum thickness of 0.5 mm. According to the model established by partial least squares discriminant analysis (PLS-DA), the important chemical marker berberine hydrochloride was obtained and analyzed quantitatively. From these results combined with chemometric and content analyses, the preliminary classification standards for phellodendron were established as three grades: superior, first-order and mixed. Compared with the traditional identification methods of thin layer chromatography identification and microscopic identification, our method for quality evaluation is relatively simple. It provides a basis and reference for identification of PCC and enables establishment of grade standards. It also could be applied in quality control for compound preparations containing PCC.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.