Evidence map›Paper›PMID 30201884›Full record

ArticleInternational journal of molecular sciences2018

Genome-Wide DNA Methylation Comparison between

Zhixin Wang, Xiangping Wu, Zengxiang Wu, Hong An, Bin Yi, Jing Wen, Chaozhi Ma, Jinxiong Shen, Tingdong Fu, Jinxing Tu

Open access · goldAbstract readComparative Study
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Whole-Genome DNA Methylation Analysis of Inoculation withJournal of fungi (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Article
  5. The Chromatin Remodeling FactorPlants (Basel, Switzerland) · 2023
    Article
  6. Epigenetic Dynamics and Regulation of Plant Male Reproduction.International journal of molecular sciences · 2022
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Zhixin WangNational Key Laboratory of Crop Genetic Improvement, College of Plant Science and Technology, National Sub-Center of Rapeseed Improvement in Wuhan, Huazhong Agricultural University, Wuhan 430070, China. watc1989@163.com.ORCID 0000-0003-2350-735X
Xiangping WuNational Key Laboratory of Crop Genetic Improvement, College of Plant Science and Technology, National Sub-Center of Rapeseed Improvement in Wuhan, Huazhong Agricultural University, Wuhan 430070, China. wuxiangp@webmail.hzau.edu.cn.
Zengxiang WuNational Key Laboratory of Crop Genetic Improvement, College of Plant Science and Technology, National Sub-Center of Rapeseed Improvement in Wuhan, Huazhong Agricultural University, Wuhan 430070, China. wuzengx@webmail.hzau.edu.cn.
Hong AnDivision of Biological Sciences, University of Missouri, Columbia, MO 65211, USA. anho@missouri.edu.ORCID 0000-0002-2367-5508
Bin YiNational Key Laboratory of Crop Genetic Improvement, College of Plant Science and Technology, National Sub-Center of Rapeseed Improvement in Wuhan, Huazhong Agricultural University, Wuhan 430070, China. yibin@mail.hzau.edu.cn.
Jing WenNational Key Laboratory of Crop Genetic Improvement, College of Plant Science and Technology, National Sub-Center of Rapeseed Improvement in Wuhan, Huazhong Agricultural University, Wuhan 430070, China. wenjing@mail.hzau.edu.cn.
Chaozhi MaNational Key Laboratory of Crop Genetic Improvement, College of Plant Science and Technology, National Sub-Center of Rapeseed Improvement in Wuhan, Huazhong Agricultural University, Wuhan 430070, China. yuanbeauty@mail.hzau.edu.cn.
Jinxiong ShenNational Key Laboratory of Crop Genetic Improvement, College of Plant Science and Technology, National Sub-Center of Rapeseed Improvement in Wuhan, Huazhong Agricultural University, Wuhan 430070, China. jxshen@mail.hzau.edu.cn.
Tingdong FuNational Key Laboratory of Crop Genetic Improvement, College of Plant Science and Technology, National Sub-Center of Rapeseed Improvement in Wuhan, Huazhong Agricultural University, Wuhan 430070, China. futing@mail.hzau.edu.cn.
Jinxing TuNational Key Laboratory of Crop Genetic Improvement, College of Plant Science and Technology, National Sub-Center of Rapeseed Improvement in Wuhan, Huazhong Agricultural University, Wuhan 430070, China. tujx@mail.hzau.edu.cn.ORCID 0000-0001-5131-4526
Huazhong Agricultural University · CNUniversity of Missouri · US

Funding

the National Key Research and Development Program of China 2016YFD0100305
6 · The paper itself

Abstract

DNA methylation is an essential epigenetic modification that dynamically regulates gene expression during plant development. However, few studies have determined the DNA methylation profiles of male-sterile rapeseed. Here, we conducted a global comparison of DNA methylation patterns between the rapeseed genic male sterile line 7365A and its near-isogenic fertile line 7365B by whole-genome bisulfite sequencing (WGBS). Profiling of the genome-wide DNA methylation showed that the methylation level in floral buds was lower than that in leaves and roots. Besides, a total of 410 differentially methylated region-associated genes (DMGs) were identified in 7365A relative to 7365B. Traditional bisulfite sequencing polymerase chain reaction (PCR) was performed to validate the WGBS data. Eleven DMGs were found to be involved in anther and pollen development, which were analyzed by quantitative PCR. In particular,

Indexed as

DNA MethylationPlant InfertilityBrassica napusFlowersGene Expression ProfilingGene Expression Regulation, PlantPlant LeavesPlant ProteinsPlant RootsWhole Genome SequencingPlant ProteinsBrassica napusfloral budgenic male sterilitywhole-genome bisulfite sequencing

Identifiers

PMID30201884
PMCPMC6165103
OpenAlexW2891815199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.