Evidence map›Paper›PMID 30201782›Full record

ArticleJournal of bacteriology2018

Connecting the Dots between Mechanosensitive Channel Abundance, Osmotic Shock, and Survival at Single-Cell Resolution.

Griffin Chure, Heun Jin Lee, Akiko Rasmussen, Rob Phillips

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A molecular rotor FLIM probe reveals dynamic coupling between mitochondrial inner membrane fluidity and cellular respiration.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  5. Life science alliance · 2023
    Article
  6. Article
  7. Article
  8. Molecular Paradigms for Biological Mechanosensing.The journal of physical chemistry. B · 2021
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Griffin Chure *Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA.ORCID 0000-0002-2216-2057
Heun Jin Lee *Department of Applied Physics, California Institute of Technology, Pasadena, California, USA.
Akiko RasmussenInstitute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom.
Rob PhillipsDepartment of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA phillips@pboc.caltech.edu.
California Institute of Technology · USUniversity of Aberdeen · GB

Funding

The Principles of Regulatory, Conformational and Evolutionary AdaptationR35GM118043 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ROB PHILLIPS · 2016 to 2026
$7.9M
NIH Director's Pioneer Award (RMI)DP1OD000217 · OD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PHILLIPS, ROB · 2004 to 2008
$4.0M
Biophysical, Structural and Functional Analysis of Mechanosensitive ChannelsR01GM084211 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI HASWELL, ELIZABETH S, PHILLIPS, ROB · 2008 to 2016
$3.6M
Single-Molecule and Single-Cell Analysis of Transcription Factor-DNA ComplexesR01GM085286 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI PHILLIPS, ROB · 2009 to 2015
$2.8M
NIGMS NIH HHS R01 GM084211NIGMS NIH HHS R01 GM085286NIGMS NIH HHS R35 GM118043NIH HHS DP1 OD000217
6 · The paper itself

Abstract

Rapid changes in extracellular osmolarity are one of many insults microbial cells face on a daily basis. To protect against such shocks,

Indexed as

BiophysicsOsmotic PressureCell MembraneEscherichia coliEscherichia coli ProteinsFluorescenceGenes, ReporterIon ChannelsMicroscopy, VideoModels, TheoreticalOsmoregulationProteomicsSingle-Cell AnalysisEscherichia coli ProteinsIon ChannelsMscL protein, E colibiophysicsmechanosensationosmoregulationquantitative methodssingle cell

Identifiers

PMID30201782
PMCPMC6222198
OpenAlexW2805367069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.