Evidence map›Paper›PMID 30201630›Full record

ArticleJournal of lipid research2018

Novel fatty acyl apoE mimetic peptides have increased potency to reduce plasma cholesterol in mice and macaques.

G M Anantharamaiah, David W Garber, Dennis Goldberg, Eric Morrel, Geeta Datta, Mayakonda N Palgunachari, Thomas C Register, Susan E Appt, C Roger White

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. HDL Mimetic Peptides.Advances in experimental medicine and biology · 2022
    Article
  6. Peptides as Therapeutic Agents for Atherosclerosis.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  7. HDL and Therapy.Advances in experimental medicine and biology · 2022
    Article
  8. Apolipoprotein E and Atherosclerosis.Current atherosclerosis reports · 2021
    Review
  9. Article
  10. Review
  11. Review
  12. Bovine HDL and Dual Domain HDL-Mimetic Peptides Inhibit Tumor Development in Mice.Journal of cancer research and therapeutic oncology · 2020
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

G M AnantharamaiahDepartment of Medicine, University of Alabama at Birmingham Medical Center, Birmingham, AL 35294.
David W GarberDepartment of Medicine, University of Alabama at Birmingham Medical Center, Birmingham, AL 35294.
Dennis GoldbergLipimetiX Development, Inc., Natick, MA 01760.
Eric MorrelLipimetiX Development, Inc., Natick, MA 01760.
Geeta DattaDepartment of Medicine, University of Alabama at Birmingham Medical Center, Birmingham, AL 35294.
Mayakonda N PalgunachariDepartment of Medicine, University of Alabama at Birmingham Medical Center, Birmingham, AL 35294.
Thomas C RegisterWake Forest School of Medicine, Winston-Salem, NC 27157.
Susan E ApptWake Forest School of Medicine, Winston-Salem, NC 27157.
C Roger WhiteDepartment of Medicine, University of Alabama at Birmingham Medical Center, Birmingham, AL 35294 crwhite@uab.edu.
University of Alabama at Birmingham · USWake Forest University · US

Funding

Wake Forest Alzheimer's Disease Core CenterP30AG049638 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ESPELAND, MARK ANDREW · 2016 to 2020
$12.2M
HDL and Cellular Repair MechanismsR01DK108836 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ANANTHARAMAIAH, G M, WHITE, C ROGER · 2016 to 2019
$1.3M
Cellular Lipids and Leukocyte FunctionR01GM115367 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ANANTHARAMAIAH, G M, WHITE, C ROGER · 2015 to 2018
$1.2M
NIA NIH HHS P30 AG049638NIDDK NIH HHS R01 DK108836NIGMS NIH HHS R01 GM115367
6 · The paper itself

Abstract

Ac-hE18A-NH

Indexed as

AnimalsApolipoproteins ECholesterolCholesterol, LDLChromatography, High Pressure LiquidElectrophoresis, Agar GelFemaleHaplorhiniHumansIntercellular Signaling Peptides and ProteinsLipid MetabolismMacacaMaleMiceMice, KnockoutPeptidesApolipoproteins ECholesterolCholesterol, LDLIntercellular Signaling Peptides and Proteinslipid-associating peptidesPeptidesapolipoprotein Edyslipidemialipoproteinslow density lipoproteinpeptides

Identifiers

PMID30201630
PMCPMC6210918
OpenAlexW2890114679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.