Evidence map›Paper›PMID 30201458›Full record

ArticleJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association2018

Improving the Accuracy of Scores to Predict Gastrostomy after Intracerebral Hemorrhage with Machine Learning.

Ravi Garg, Shyam Prabhakaran, Jane L Holl, Yuan Luo, Roland Faigle, Konrad Kording, Andrew M Naidech

Abstract read
In one paragraph

Article in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ravi GargCenter for Healthcare Studies, Northwestern University, Chicago, Illinois.
Shyam PrabhakaranCenter for Healthcare Studies, Northwestern University, Chicago, Illinois.
Jane L HollCenter for Healthcare Studies, Northwestern University, Chicago, Illinois.
Yuan LuoDepartment of Preventive Medicine, Northwestern University, Chicago, Illinois.
Roland FaigleDepartment of Neurology, Johns Hopkins University, Baltimore, Maryland.
Konrad KordingDepartment of Neuroscience, University of Pennsylvania, Pennsylvania.
Andrew M NaidechCenter for Healthcare Studies, Northwestern University, Chicago, Illinois. Electronic address: a-naidech@northwestern.edu.
Northwestern University · USJohns Hopkins University · USUniversity of Pennsylvania · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Multidisciplinary Clinical and Translational Science (MCTS) Program (UL1)UL1TR000150 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LLOYD-JONES, DONALD M · 2012 to 2013
$10.1M
Mechanisms underlying race disparities in gastrostomy placement after strokeK23NS101124 · NINDS · JOHNS HOPKINS UNIVERSITY · PI FAIGLE, ROMANUS ROLAND · 2017 to 2020
$799k
Bayesian Generative Methods for Extracting and Modeling Relations in EHR NarrativesR21LM012618 · NLM · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LUO, YUAN · 2017 to 2018
$390k
Health related quality of life and seizure medications after hemorrhagic strokeK18HS023437 · AHRQ · NORTHWESTERN UNIVERSITY AT CHICAGO · PI NAIDECH, ANDREW M · 2015 to 2016
$357k
AHRQ HHS K18 HS023437NCATS NIH HHS UL1 TR000150NCATS NIH HHS UL1 TR001422NINDS NIH HHS K23 NS101124NLM NIH HHS R21 LM012618
6 · The paper itself

Abstract

backgroundGastrostomy placement after intracerebral hemorrhage indicates the need for continued medical care and predicts patient dependence. Our objective was to determine the optimal machine learning technique to predict gastrostomy.

methodsWe included 531 patients in a derivation cohort and 189 patients from another institution for testing. We derived and tested predictions of the likelihood of gastrostomy placement with logistic regression using the GRAVo score (composed of Glasgow Coma Scale ≤12, age >50 years, black race, and hematoma volume >30 mL), compared to other machine learning techniques (kth nearest neighbor, support vector machines, random forests, extreme gradient boosting, gradient boosting machine, stacking). Receiver Operating Curves (Area Under the Curve, [AUC]) between logistic regression (the technique used in GRAVo score development) and other machine learning techniques were compared. Another institution provided an external test data set.

resultsIn the external test data set, logistic regression using the GRAVo score components predicted gastrostomy (P < 0.001), however, with a lower AUC (0.66) than kth nearest neighbors (AUC 0.73), random forests (AUC 0.74), Gradient boosting machine (AUC 0.77), extreme gradient boosting (AUC 0.77), (P < 0.01 for all compared to logistic regression). Results from the internal test set were similar.

conclusionsMachine learning techniques other than logistic regression (eg, random forests, extreme gradient boost, and kth nearest neighbors) were significantly more accurate for predicting gastrostomy using the same independent variables. Machine learning techniques may assist clinicians in identifying patients likely to need interventions.

Indexed as

GastrostomyMachine LearningAgedCerebral HemorrhageHumansPrognosisProspective StudiesIntracerebral hemorrhage—gastrostomy—outcomes—machine learning

Identifiers

PMID30201458
PMCPMC6252136
OpenAlexW2889887438

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.