ArticleUrology2018
Diagnostic Accuracy of a Rapid Biparametric MRI Protocol for Detection of Histologically Proven Prostate Cancer.
Article in Urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06071195 (All-in-One Prostate Cancer Staging with MRI), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
All-in-One Prostate Cancer Staging with MRI
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis of the diagnostic accuracy of biparametric prostate MRI for prostate cancer in men at risk.Prostate cancer and prostatic diseases · 2021Pooled it
- Global Cancer Imaging Access: Addressing Barriers and Harnessing Innovations.Radiology. Imaging cancer · 2025Review
- Biparametric MRI-based radiomics for prediction of clinically significant prostate cancer of PI-RADS category 3 lesions.BMC cancer · 2025Article
- Biparametric MRI-based radiomics for differentiating clinically significant prostate cancer among prostate-specific antigen level of gray zone.Frontiers in oncology · 2025Article
- Comparisons of three scoring systems based on biparametric magnetic resonance imaging for prediction of clinically significant prostate cancer.Prostate international · 2024Article
- Optimizing Multiparametric MRI Protocols for Prostate Cancer Detection: A Comprehensive Assessment Aligned with PI-RADS Guidelines.Health science reports · 2024Article
- Article
- Dynamic Contrast-Enhanced Study in the mpMRI of the Prostate-Unnecessary or Underutilised? A Narrative Review.Diagnostics (Basel, Switzerland) · 2023Review
- Current Status of Biparametric MRI in Prostate Cancer Diagnosis: Literature Analysis.Life (Basel, Switzerland) · 2022Review
- Bi-parametric MRI/TRUS fusion targeted repeat biopsy after systematic 10-12 core TRUS-guided biopsy reveals more significant prostate cancer especially in anteriorly located tumors.Acta radiologica open · 2022Article
- Diagnostic Accuracy of Abbreviated Bi-Parametric MRI (a-bpMRI) for Prostate Cancer Detection and Screening: A Multi-Reader Study.Diagnostics (Basel, Switzerland) · 2022Article
- The Utility of Combined Target and Systematic Prostate Biopsies in the Diagnosis of Clinically Significant Prostate Cancer Using Prostate Imaging Reporting and Data System Version 2 Based on Biparametric Magnetic Resonance Imaging.Current oncology (Toronto, Ont.) · 2021Article
- Round table: arguments in supporting abbreviated or biparametric MRI of the prostate protocol.Abdominal radiology (New York) · 2020Review
- Biparametric versus multiparametric magnetic resonance imaging of the prostate: detection of clinically significant cancer in a perfect match group.Prostate international · 2020Article
- Rectal gas-induced susceptibility artefacts on prostate diffusion-weighted MRI with epi read-out at 3.0 T: does a preparatory micro-enema improve image quality?Abdominal radiology (New York) · 2020Article
- How Fast Can We Go: Abbreviated Prostate MR Protocols.Current urology reports · 2020Review
- [Contrast-agent free imaging of the prostate : Ready for clinical practice?]Der Radiologe · 2019Review
- The role of gadolinium in magnetic resonance imaging for early prostate cancer diagnosis: A diagnostic accuracy study.PloS one · 2019Article
- Simplified PI-RADS with Biparametric MRI: A Practical Approach to Improve Management of PI-RADS Version 2 Category 3 Lesions.Radiology · 2018Article
- Short review of biparametric prostate MRI.Memo · 2018Review
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
objectiveTo evaluate the performance of a rapid, low cost, noncontrast MRI examination as a secondary screening tool in detection of clinically significant prostate cancer.
methodsIn this prospective single institution study, 129 patients with elevated prostate-specific antigen levels or abnormal digital rectal examination findings underwent MRI with an abbreviated biparamatric MRI protocol consisting of high-resolution axial T2- and diffusion-weighted images. Index lesions were classified according to modified Prostate Imaging - Reporting and Data System (mPI-RADS) version 2.0. All patients underwent standard transrectal ultrasound-guided biopsy after MRI with the urologist being blinded to MRI results. Subsequently, all patients with suspicious lesions (mPI-RADS 3, 4, or 5) underwent cognitively guided targeted biopsy after discussion of MRI results with the urologist. Sensitivity and negative predictive value for identification of clinically significant prostate cancer (Gleason score 3+4 and above) were determined.
resultsRapid biparametric MRI discovered 176 lesions identified in 129 patients. Rapid MRI detected clinically significant cancers with a sensitivity of 95.1% with a negative predictive value of 95.1% and positive predictive value of 53.2%, leading to a change in management in 10.8% of the patients. False negative rate of biparametric (bp) MRI was 4.7%.
conclusionWe found that a bp-MRI examination can detect clinically significant lesions and changed patient management in 10.8% of the patients. A rapid MRI protocol can be used as a useful secondary screening tool in men presenting with suspicion of prostate cancer.
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