Evidence map›Paper›PMID 30201054›Full record

Trial reportBMC research notes2018

Medical and social costs after using financial incentives to improve medication adherence: results of a 1 year randomised controlled trial.

Ernst L Noordraven, André I Wierdsma, Peter Blanken, Anthony F T Bloemendaal, Cornelis L Mulder

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ernst L NoordravenDual Diagnosis Center (CDP) Palier, Parnassia Psychiatric Institute, 2552 KS, The Hague, The Netherlands. e.noordraven@erasmusmc.nl.ORCID http://orcid.org/0000-0003-4287-7647
André I WierdsmaDepartment of Psychiatry, Erasmus University Medical Center, Epidemiological and Social Psychiatric Research Institute, 3015 CE, Rotterdam, The Netherlands.
Peter BlankenParnassia Addiction Research Centre (PARC), Brijder Addiction Treatment, Parnassia Psychiatric Institute, 2553 RJ, The Hague, The Netherlands.
Anthony F T BloemendaalDual Diagnosis Center (CDP) Palier, Parnassia Psychiatric Institute, 2552 KS, The Hague, The Netherlands.
Cornelis L MulderDepartment of Psychiatry, Erasmus University Medical Center, Epidemiological and Social Psychiatric Research Institute, 3015 CE, Rotterdam, The Netherlands.
Erasmus MC · NLParnassia Groep · NL

Funding

Multiplexed single-cell contractility assay to develop therapeutics for asthma and hypertensionR43TR002350 · NCATS · FORCYTE BIOTECHNOLOGIES, INC. · PI PUSHKARSKY, IVAN · 2018 to 2018
$225k
NCATS NIH HHS R43 TR002350
6 · The paper itself

Abstract

objectiveOffering a financial incentive ('Money for Medication') is effective in improving adherence to treatment with depot antipsychotic medications. We investigated the cost-effectiveness in terms of medical costs and judicial expenses of using financial incentives to improve adherence. The effects of financial incentives on depot medication adherence were evaluated in a randomised controlled trial. Patients in the intervention group received €30 a month over 12 months if antipsychotic depot medication was accepted. The control group received mental health care as usual. For 133 patients outcomes were calculated based on self-reported service use and delinquent behaviour and expressed as standard unit costs to value resource use.

resultsThe financial incentive resulted in higher average costs related to mental health care (€449.6 versus €355.7). and lower medical costs related to other healthcare services (€52.0 versus €78.4). Relevant differences in social costs related to delinquent behaviour were not found. Although wide confidence intervals indicate uncertainty, incremental cost-effectiveness ratio's (ICER) indicate that it costs €2080 for achieving a 20% increase in adherence or €3332 for achieving over 80% adherence. In sum, offering money as financial incentive for increasing compliance did not lead to an overall cost reduction as compared to care as usual. Trial registration NTR2350, 01 June 2010.

Indexed as

Financing, PersonalHealth Care CostsMedication AdherenceMotivationPsychotic DisordersAntipsychotic AgentsCost-Benefit AnalysisDrug CostsHumansAntipsychotic AgentsAdherenceAntipsychoticsFinancial incentivesHealth care costsPsychosis

Identifiers

PMID30201054
PMCPMC6131864
OpenAlexW2890031851

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.