Evidence map›Paper›PMID 30200901›Full record

ArticleBMC bioinformatics2018

SuperNoder: a tool to discover over-represented modular structures in networks.

Danilo Dessì, Jacopo Cirrone, Diego Reforgiato Recupero, Dennis Shasha

Abstract read
In one paragraph

Article in BMC bioinformatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Danilo DessìDepartment of Mathematics and Computer Science, University of Cagliari, Cagliari, 09124, Italy. danilo_dessi@unica.it.ORCID http://orcid.org/0000-0003-3843-3285
Jacopo CirroneDepartment of Computer Science, Courant Institute of Mathematical Sciences, New York University, New York City, 10012, USA.
Diego Reforgiato RecuperoDepartment of Mathematics and Computer Science, University of Cagliari, Cagliari, 09124, Italy.
Dennis ShashaDepartment of Computer Science, Courant Institute of Mathematical Sciences, New York University, New York City, 10012, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNetworks whose nodes have labels can seem complex. Fortunately, many have substructures that occur often ("motifs"). A societal example of a motif might be a household. Replacing such motifs by named supernodes reduces the complexity of the network and can bring out insightful features. Doing so repeatedly may give hints about higher level structures of the network. We call this recursive process Recursive Supernode Extraction.

resultsThis paper describes algorithms and a tool to discover disjoint (i.e. non-overlapping) motifs in a network, replacing those motifs by new nodes, and then recursing. We show applications in food-web and protein-protein interaction (PPI) networks where our methods reduce the complexity of the network and yield insights.

conclusionsSuperNoder is a web-based and standalone tool which enables the simplification of big graphs based on the reduction of high frequency motifs. It applies various strategies for identifying disjoint motifs with the goal of enhancing the understandability of networks.

Indexed as

AlgorithmsMetabolic Networks and PathwaysProtein Interaction MapsSoftwareComputational BiologyHumansComputational complexityFood-web networkMotifs discoveryNetwork compressionPPI interaction network

Identifiers

PMID30200901
PMCPMC6131773

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.