Evidence map›Paper›PMID 30200668›Full record

ReviewInternational journal of molecular sciences2018

Structure-Based Classification and Anti-Cancer Effects of Plant Metabolites.

Seong-Ah Shin, Sun Young Moon, Woe-Yeon Kim, Seung-Mann Paek, Hyun Ho Park, Chang Sup Lee

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Article
  3. Molecular Mechanisms of Vitexin: An Update on Its Anti-Cancer Functions.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Plant Metabolomics: The Future of Anticancer Drug Discovery.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  6. Review
  7. [The role and the molecular mechanism of abietic acid in the proliferation, invasion and migration of cisplatin-resistant nasopharyngeal carcinoma cells].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024
    Article
  8. Article
  9. Review
  10. The Role and Mechanism ofMolecules (Basel, Switzerland) · 2023
    Review
  11. Article
  12. Review
  13. Pharmaceutical biology · 2022
    Article
  14. Fermented Mangosteen (Cancers · 2022
    Article
  15. Review
  16. Molecules (Basel, Switzerland) · 2022
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Seong-Ah ShinCollage of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Korea. shinsaya@gnu.ac.kr.
Sun Young MoonCollage of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Korea. symoon0414@gnu.ac.kr.
Woe-Yeon KimDivision of Applied Life Science (BK21Plus), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Research Institute of Life Sciences (RILS), Gyeongsang National University, Jinju 52828, Korea. kim1312@gnu.ac.kr.
Seung-Mann PaekCollage of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Korea. million@gnu.ac.kr.
Hyun Ho ParkCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea. xrayleox@cau.ac.kr.ORCID 0000-0001-9928-0847
Chang Sup LeeCollage of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Korea. changsup@gnu.ac.kr.

Funding

Rural Development Administration PJ01327302
6 · The paper itself

Abstract

A variety of malignant cancers affect the global human population. Although a wide variety of approaches to cancer treatment have been studied and used clinically (surgery, radiotherapy, chemotherapy, and immunotherapy), the toxic side effects of cancer therapies have a negative impact on patients and impede progress in conquering cancer. Plant metabolites are emerging as new leads for anti-cancer drug development. This review summarizes these plant metabolites with regard to their structures and the types of cancer against which they show activity, organized by the organ or tissues in which each cancer forms. This information will be helpful for understanding the current state of knowledge of the anti-cancer effects of various plant metabolites against major types of cancer for the further development of novel anti-cancer drugs.

Indexed as

Antineoplastic Agents, PhytogenicCell Line, TumorCell ProliferationCell SurvivalHumansNeoplasmsPlant ExtractsPlantsStructure-Activity RelationshipAntineoplastic Agents, PhytogenicPlant Extractsanti-cancer drugcancermetaboliteplant

Identifiers

PMID30200668
PMCPMC6163735

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.