Evidence map›Paper›PMID 30200664›Full record

ArticleMarine drugs2018

Marine Microalgae: Promising Source for New Bioactive Compounds.

Caterina R de Vera, Guillermo Díaz Crespín, Antonio Hernández Daranas, Sofia Montalvão Looga, Katja-Emilia Lillsunde, Päivi Tammela, Merja Perälä, Vesa Hongisto, Johannes Virtanen, Heiko Rischer and 4 more

Abstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Marine drugs · 2023
    Review
  6. Article
  7. Biostimulant activity ofFrontiers in plant science · 2023
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Potential of the Red AlgaPlants (Basel, Switzerland) · 2021
    Article
  13. Review
  14. Nutritional Potential and Toxicological Evaluation ofMolecules (Basel, Switzerland) · 2019
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Caterina R de VeraInstituto Universitario de Bio-Orgánica Antonio González (IUBO AG), Centro de Investigaciones Biomédicas de Canarias (CIBICAN), Universidad de La Laguna (ULL), Avenida Astrofísico Francisco Sánchez 2, 38206 Tenerife, Spain. caterina.rdv@gmail.com.ORCID 0000-0002-9750-2052
Guillermo Díaz CrespínInstituto Universitario de Bio-Orgánica Antonio González (IUBO AG), Centro de Investigaciones Biomédicas de Canarias (CIBICAN), Universidad de La Laguna (ULL), Avenida Astrofísico Francisco Sánchez 2, 38206 Tenerife, Spain. gdiazcrespin09@gmail.com.ORCID 0000-0001-8169-5403
Antonio Hernández DaranasInstituto Universitario de Bio-Orgánica Antonio González (IUBO AG), Centro de Investigaciones Biomédicas de Canarias (CIBICAN), Universidad de La Laguna (ULL), Avenida Astrofísico Francisco Sánchez 2, 38206 Tenerife, Spain. adaranas@ipna.csic.es.
Sofia Montalvão LoogaDrug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, P.O. Box 56, University of Helsinki, FI-00014 Helsinki, Finland. sofiaimontalvao@gmail.com.
Katja-Emilia LillsundeDrug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, P.O. Box 56, University of Helsinki, FI-00014 Helsinki, Finland. katja-emilia.lillsunde@helsinki.fi.
Päivi TammelaDrug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, P.O. Box 56, University of Helsinki, FI-00014 Helsinki, Finland. paivi.tammela@helsinki.fi.ORCID 0000-0003-4697-8066
Merja PeräläVTT Technical Research Centre of Finland Ltd., P.O. Box 1000, FI-02044 Espoo, Finland. merja.perala@auriabiopankki.fi.
Vesa HongistoVTT Technical Research Centre of Finland Ltd., P.O. Box 1000, FI-02044 Espoo, Finland. Hongisto@misvik.com.
Johannes VirtanenVTT Technical Research Centre of Finland Ltd., P.O. Box 1000, FI-02044 Espoo, Finland. johannes.hattara@gmail.com.
Heiko RischerVTT Technical Research Centre of Finland Ltd., P.O. Box 1000, FI-02044 Espoo, Finland. heiko.rischer@vtt.fi.ORCID 0000-0002-8004-4526
Christian D MullerInstitut Pluridisciplinaire Hubert Curien, UMR 7178 CRNS, Faculté de Pharmacie, Université de Strasbourg, 67401 Illkirch, France. cdmuller@unistra.fr.ORCID 0000-0002-3463-1025
Manuel NorteInstituto Universitario de Bio-Orgánica Antonio González (IUBO AG), Centro de Investigaciones Biomédicas de Canarias (CIBICAN), Universidad de La Laguna (ULL), Avenida Astrofísico Francisco Sánchez 2, 38206 Tenerife, Spain. mnorte@ull.edu.es.
José J FernándezInstituto Universitario de Bio-Orgánica Antonio González (IUBO AG), Centro de Investigaciones Biomédicas de Canarias (CIBICAN), Universidad de La Laguna (ULL), Avenida Astrofísico Francisco Sánchez 2, 38206 Tenerife, Spain. jjfercas@ull.edu.es.
María L SoutoInstituto Universitario de Bio-Orgánica Antonio González (IUBO AG), Centro de Investigaciones Biomédicas de Canarias (CIBICAN), Universidad de La Laguna (ULL), Avenida Astrofísico Francisco Sánchez 2, 38206 Tenerife, Spain. msouto@ull.edu.es.

Funding

Academy of Finland 277001Ministerio de Economía y Competitividad CTQ2014-55888-C03-01Seventh Framework Programme EU FP7-KBBE-3-245137 (MAREX)
6 · The paper itself

Abstract

The study of marine natural products for their bioactive potential has gained strength in recent years. Oceans harbor a vast variety of organisms that offer a biological and chemical diversity with metabolic abilities unrivalled in terrestrial systems, which makes them an attractive target for bioprospecting as an almost untapped resource of biotechnological applications. Among them, there is no doubt that microalgae could become genuine "cell factories" for the biological synthesis of bioactive substances. Thus, in the course of inter-laboratory collaboration sponsored by the European Union (7th FP) into the MAREX Project focused on the discovery of novel bioactive compounds of marine origin for the European industry, a bioprospecting study on 33 microalgae strains was carried out. The strains were cultured at laboratory scale. Two extracts were prepared for each one (biomass and cell free culture medium) and, thus, screened to provide information on the antimicrobial, the anti-proliferative, and the apoptotic potential of the studied extracts. The outcome of this study provides additional scientific data for the selection of

Indexed as

BioprospectingDrug DiscoveryAnti-Bacterial AgentsApoptosisBiological FactorsBiotechnologyCell ProliferationMicroalgaeOceans and SeasAnti-Bacterial AgentsBiological Factorsbioactive compoundbioprospectingblue biotechnologydrug discoverymarine microalgaemarine natural products

Identifiers

PMID30200664
PMCPMC6164378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.