Evidence map›Paper›PMID 30200660›Full record

ArticleInternational journal of molecular sciences2018

Mechanism of Lakoochin A Inducing Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS and MAPKs Pathway.

Kuo-Ti Peng, Yao-Chang Chiang, Horng-Huey Ko, Pei-Ling Chi, Chia-Lan Tsai, Ming-I Ko, Ming-Hsueh Lee, Lee-Fen Hsu, Chiang-Wen Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Pharmacological effects ofPharmaceutical biology · 2022
    Article
  3. Suppressive role of Viola odorata extract on malignant characters of mammosphere-derived breast cancer stem cells.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Kuo-Ti PengDepartment of Orthopaedic Surgery, Chang Gung Memorial Hospital, Puzi City, Chiayi County 61363, Taiwan. mr3497@adm.cgmh.org.tw.
Yao-Chang ChiangDepartment of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Puzi City, Chiayi County 61363, Taiwan. yaochang.chiang@gmail.com.ORCID 0000-0002-7619-1902
Horng-Huey KoDepartment of Fragrance and Cosmetic Science, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan. hhko@kmu.edu.tw.
Pei-Ling ChiDepartment of Medical Education and Research, Kaohsiung Veterans General Hospital, Zuoying Dist., Kaohsiung City 81362, Taiwan. chi542738@gmail.com.
Chia-Lan TsaiDepartment of Nursing, Division of Basic Medical Sciences, Chang Gung University of Science and Technology, Guishan Dist., Taoyuan City 33303, Taiwan. cltsai@mail.cgust.edu.tw.
Ming-I KoDepartment of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Puzi City, Chiayi County 61363, Taiwan. s041055@mail.cgust.edu.tw.
Ming-Hsueh LeeDivision of Neurosurgery, Department of Surgery, Chang Gung Memorial Hospital, Puzi City, Chiayi County 61363, Taiwan. ma2072@gmail.com.
Lee-Fen HsuDivision of Neurosurgery, Department of Surgery, Chang Gung Memorial Hospital, Puzi City, Chiayi County 61363, Taiwan. lfhsu@mail.cgust.edu.tw.
Chiang-Wen LeeDepartment of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Puzi City, Chiayi County 61363, Taiwan. cwlee@mail.cgust.edu.tw.
Chang Gung University of Science and Technology · TWChang Gung University · TWKaohsiung Medical University · TWKaohsiung Veterans General Hospital · TW

Funding

Chang Gung Medical Foundation CMRPF6E0031, CMRPF6E0032, CMRPF6E0033 and CMRPF6G0021
6 · The paper itself

Abstract

Malignant melanoma is developed from pigment-containing cells, melanocytes, and primarily found on the skin. Malignant melanoma still has a high mortality rate, which may imply a lack of therapeutic agents. Lakoochin A, a compound isolated from

Indexed as

Antineoplastic Agents, PhytogenicCaspasesCell Line, TumorCell ProliferationCell SurvivalGene Expression Regulation, NeoplasticHumansMAP Kinase Signaling SystemMelanomaMitochondriaReactive Oxygen SpeciesStilbenesAntineoplastic Agents, PhytogenicCaspaseslakoochin AReactive Oxygen SpeciesStilbenesapoptosislakoochin AMAPKsmelanoma cellsmitochondriapro-oxidation

Identifiers

PMID30200660
PMCPMC6164788
OpenAlexW2891636992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.