Evidence map›Paper›PMID 30200629›Full record

ReviewGenes2018

Can Genetic Factors Compromise the Success of Dental Implants? A Systematic Review and Meta-Analysis.

Joel Ferreira Santiago Junior, Claudia Cristina Biguetti, Mariza Akemi Matsumoto, Guilherme Abu Halawa Kudo, Raquel Barroso Parra da Silva, Patrícia Pinto Saraiva, Walid D Fakhouri

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Genes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Association ofInternational journal of environmental research and public health · 2021
    Pooled it
  3. Pooled it
  4. Observational
  5. Article
  6. Article
  7. Association betweenPathogens (Basel, Switzerland) · 2021
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Joel Ferreira Santiago JuniorPró⁻Reitoria de Pesquisa e Pós-graduação (PRPPG), Universidade do Sagrado Coração, USC, 10⁻50 Irmã Arminda, Jardim Brasil, Bauru, SP 17011⁻160, Brazil. Jf.santiagojunior@gmail.com.
Claudia Cristina BiguettiDepartment of Basic Sciences, São Paulo State University (Unesp), School of Dentistry, Araçatuba, SP 16015-050, Brazil. klaudiabiguetti@gmail.com.
Mariza Akemi MatsumotoDepartment of Basic Sciences, São Paulo State University (Unesp), School of Dentistry, Araçatuba, SP 16015-050, Brazil. vicmak.blv@terra.com.br.
Guilherme Abu Halawa KudoPró⁻Reitoria de Pesquisa e Pós-graduação (PRPPG), Universidade do Sagrado Coração, USC, 10⁻50 Irmã Arminda, Jardim Brasil, Bauru, SP 17011⁻160, Brazil. Guilherme_kudo@hotmail.com.
Raquel Barroso Parra da SilvaDepartment of Basic Sciences, São Paulo State University (Unesp), School of Dentistry, Araçatuba, SP 16015-050, Brazil. raque_parra@hotmail.com.
Patrícia Pinto SaraivaPró⁻Reitoria de Pesquisa e Pós-graduação (PRPPG), Universidade do Sagrado Coração, USC, 10⁻50 Irmã Arminda, Jardim Brasil, Bauru, SP 17011⁻160, Brazil. ppbau@uol.com.br.ORCID 0000-0002-2454-3996
Walid D FakhouriCenter for Craniofacial Research, Department of Diagnostic and Biomedical Sciences, School of Dentistry, University of Texas Health Science Center at Houston, Houston, TX 77054, USA. Walid.D.Fakhouri@uth.tmc.edu.ORCID 0000-0002-2199-3828
Universidade Estadual Paulista (Unesp) · BRUniversidade Sagrado Coração · BRThe University of Texas Health Science Center at Houston · US

Funding

Modeling of pathological significance of non-coding DNA variants in cis-overlapping motifs of p53 and cMycR15GM122030 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FAKHOURI, WALID D. · 2016 to 2016
$476k
NIH HHS GM122030-01Research Foundation of the State of São Paulo 2015/20827-2Research Foundation of the State of São Paulo 2017/13276-5
6 · The paper itself

Abstract

Dental implants provide a predictable treatment option for partial and complete edentulism via the placement of a fixed permanent artificial root to support prosthetic dental crowns. Despite the high survival rates, long-term dental implant failures are still reported, leading to implant removals and additional financial and health burdens. While extrinsic factors that improve the success rate of implants have been well explored, the impact of genetic factors on this matter is poorly understood. A systematic review and meta-analysis study was conducted to determine whether genetic factors contribute to an increased risk of dental implant failures. A comprehensive search for peer-reviewed articles on dental implants and genetic factors was performed using various literature database libraries. The study design was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, and the obtained records were registered in the International Prospective Register of Systematic Reviews (PROSPERO) database. According to the exclusion/inclusion criteria, 13 studies were eligible for this study out of 809 articles. The meta-analysis of the combined association studies of DNA variations and dental implants did not indicate an increased risk for implant failure due to DNA variations in

Indexed as

bone qualitybone regenerationdental implantsgenetic factorssurvival rate

Identifiers

PMID30200629
PMCPMC6162655
OpenAlexW2884667641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.