Evidence map›Paper›PMID 30200426›Full record

ArticleToxins2018

Enterohemorrhagic

C Ming Tse, Julie G In, Jianyi Yin, Mark Donowitz, Michele Doucet, Jennifer Foulke-Abel, Fernando Ruiz-Perez, James P Nataro, Nicholas C Zachos, James B Kaper and 1 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. EnteroaggregativeEcoSal Plus · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. The Diversity ofMicroorganisms · 2023
    Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. IgG BindsFrontiers in immunology · 2022
    Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

C Ming TseDepartment of Medicine, Division of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. mtse@jhmi.edu.
Julie G InDepartment of Medicine, Division of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. jgin@salud.unm.edu.
Jianyi YinDepartment of Medicine, Division of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. jianyi.yin@outlook.com.
Mark DonowitzDepartment of Medicine, Division of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. mdonowit@jhmi.edu.
Michele DoucetDepartment of Medicine, Division of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. mdoucet2@jhmi.edu.
Jennifer Foulke-AbelDepartment of Medicine, Division of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. jfoulke@jhmi.edu.ORCID 0000-0003-3882-5625
Fernando Ruiz-PerezDepartment of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA. FR3D@hscmail.mcc.virginia.edu.
James P NataroDepartment of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA. JPN2R@hscmail.mcc.virginia.edu.
Nicholas C ZachosDepartment of Medicine, Division of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. nzachos1@jhmi.edu.
James B KaperDepartment of Microbiology & Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. JKaper@som.umaryland.edu.
Olga KovbasnjukDepartment of Medicine, Division of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. OKovbasnjuk@salud.unm.edu.
Johns Hopkins University · USUniversity of Virginia · USUniversity of Maryland, Baltimore · US

Funding

Project 3 - Human colonoids as a model for the pathobiology of EHECP01AI125181 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI KAPER, JAMES B · 2016 to 2025
$18.6M
Translational Research Enhancement CoreP30DK089502 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI ZACHOS, NICHOLAS CONSTANTINE · 2011 to 2020
$12.0M
Translational Approaches to Develop Drug Therapy for DiarrheaR24DK099803 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI DONOWITZ, MARK · 2014 to 2019
$8.9M
DIARRHEAL DISEASES: A PHYSIOLOGIC APPROACH TO TREATMENTR01DK026523 · NIDDK · TUFTS MEDICAL CENTER · PI DONOWITZ, MARK · 1986 to 2016
$7.8M
Human Enteroids as a Model of Host-EHEC InteractionsK01DK106323 · NIDDK · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI IN, JULIE GOEUN · 2016 to 2020
$711k
NIAID NIH HHS P01 AI125181NIDDK NIH HHS K01 DK106323NIDDK NIH HHS P30 DK089502NIDDK NIH HHS R01 DK026523NIDDK NIH HHS R24 DK099803
6 · The paper itself

Abstract

One of the characteristic manifestations of Shiga-toxin-producing

Indexed as

Bacterial ToxinsColonEnterohemorrhagic Escherichia coliEscherichia coli ProteinsHumansIon TransportOrganoidsSerine EndopeptidasesBacterial ToxinsEscherichia coli ProteinsEspP protein, E coliSerine EndopeptidasesCFTRdiarrheaEHEChuman colonoid monolayersintracellular Ca2+serine protease EspPshort circuit currentSPATEs

Identifiers

PMID30200426
PMCPMC6162544
OpenAlexW2891625643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.