ArticleNanomaterials (Basel, Switzerland)2018
Development of Magnetically Active Scaffolds for Bone Regeneration.
Article in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Magnetoelectric PVDF-Cobalt Ferrite Films: Magnetostrictive and Magnetorotational Effects, Synergy, and Counteraction.Nanomaterials (Basel, Switzerland) · 2025Article
- Magnetostrictive and Magnetoactive Effects in Piezoelectric Polymer Composites.Nanomaterials (Basel, Switzerland) · 2023Article
- Biomaterial-assisted tumor therapy: A brief review of hydroxyapatite nanoparticles and its composites used in bone tumors therapy.Frontiers in bioengineering and biotechnology · 2023Review
- Magnetoelectric effect: principles and applications in biology and medicine- a review.Materials today. Bio · 2021Review
- Low Crystallinity of Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) Bioproduction by Hot Spring CyanobacteriumPlants (Basel, Switzerland) · 2021Article
- Recent Advances of Magnetic Nanomaterials in Bone Tissue Repair.Frontiers in chemistry · 2020Review
- 3D Cytocompatible Composites of PCL/magnetite.Materials (Basel, Switzerland) · 2019Article
- The Contribution of Magnetic Nanoparticles to Ferrogel Biophysical Properties.Nanomaterials (Basel, Switzerland) · 2019Article
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Authors and funding
5 authors.
Funding
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Abstract
This work reports on the synthesis, with the thermally induced phase separation (TIPS) technique, of poly (l-lactide) (PLLA) scaffolds containing Fe-doped hydroxyapatite (FeHA) particles for bone regeneration. Magnetization curves and X-ray diffraction indicate two magnetic particle phases: FeHA and magnetite Fe₃O₄. Magnetic nanoparticles (MNPs) are approximately 30 ± 5 nm in width and 125 ± 25 nm in length, and show typical ferromagnetic properties, including coercivity and rapid saturation magnetization. Scanning electron microscopy (SEM) images of the magnetic scaffolds reveal their complex morphology changes with MNP concentration. Similarly, at compositions of approximately 20% MNPs, the phase separation changes, passing from solid⁻liquid to liquid⁻liquid as revealed by the hill-like structures, with low peaks that give the walls in the SEM images a surface pattern of micro-ruggedness typical of nucleation mechanisms and growth. In vitro degradation experiments, carried out for more than 28 weeks, demonstrated that the MNPs delay the scaffold degradation process. Cytotoxicity is appreciated for FeHA content above 20%.
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Registered trials
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