ArticlePloS one2018
Multiple insecticide resistance mechanisms in primary dengue vector, Aedes aegypti (Linn.) from dengue endemic districts of sub-Himalayan West Bengal, India.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 54 citations in OpenAlex.
- Emerging and regionally novel voltage-gated sodium channel mutations associated with pyrethroid resistance and altered binding affinity in Aedes albopictus (Skuse) from Northern Peninsular Malaysia.Parasites & vectors · 2026Article
- Cytochrome P450 Monooxygenase Mediated Pyrethroid Resistance in the Urban Dengue Vector, Aedes aegypti (Diptera: Culicidae) from Northern Part of West Bengal, India.Acta parasitologica · 2026Article
- Presence of localized elevated metabolic enzymes and kdr mutations in the voltage-gated sodium channel gene indicate early evidence of resistance of Phlebotomus argentipes to alpha-cypermethrin in Bihar, India.Parasites & vectors · 2026Article
- Laboratory Evaluation of Susceptibility Status of Aedes aegypti Mosquitoes to Temephos and Bacillus thuringiensis israelensis (Bti) Toxins from Odisha, India.Acta parasitologica · 2026Article
- Resistance status ofNarra J · 2025Review
- Larvicidal and enzyme inhibition effects of Phoenix pusilla derived Methyl oleate and malathion on Aedes aegypti strains.Scientific reports · 2024Article
- Antiviral Effect of MicroalgaeMarine drugs · 2024Article
- Evaluation of diflubenzuron-verapamil combination strategy for eco-safe management ofFrontiers in physiology · 2024Article
- Article
- Worldwide Status of Insecticide Resistance ofJournal of arthropod-borne diseases · 2023Review
- Larvicidal proficiency of volatile compounds present inFrontiers in plant science · 2023Article
- First report of F1534C kdr mutation in deltamethrin resistant Aedes albopictus from northern part of West Bengal, India.Scientific reports · 2022Article
- Elimination of a closed population of the yellow fever mosquito, Aedes aegypti, through releases of self-limiting male mosquitoes.PLoS neglected tropical diseases · 2022Article
- Untargeted metabolomics-based response analysis of temperature and insecticide exposure in Aedes aegypti.Scientific reports · 2022Article
- Fabrication and characterization of noble crystalline silver nanoparticles fromSaudi journal of biological sciences · 2022Article
- Rapid evolution of knockdown resistance haplotypes in response to pyrethroid selection inEvolutionary applications · 2021Article
- Phenotypic and haplotypic profiles of insecticide resistance in populations of Aedes aegypti larvae (Diptera: Culicidae) from central Lao PDR.Tropical medicine and health · 2021Article
- A new knockdown resistance (kdr) mutation, F1534L, in the voltage-gated sodium channel of Aedes aegypti, co-occurring with F1534C, S989P and V1016G.Parasites & vectors · 2020Article
- Monitoring Insecticide Susceptibility inTropical medicine and infectious disease · 2020Article
- Impact of deltamethrin selection on kdr mutations and insecticide detoxifying enzymes in Aedes aegypti from Mexico.Parasites & vectors · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMosquitoes belonging to genus Aedes are the prime vectors of several arboviral diseases such as Dengue, Zika and Chikungunya worldwide. Every year numerous cases of dengue infections occur throughout the world, proper control of which depends on efficient vector control. However the onset of insecticide resistance has resulted in failure of vector control approaches. PRINCIPAL
findingsThis study was carried out to unveil the degree of prevailing insecticide resistance along with its underlying mechanisms among the primary dengue vector in dengue endemic districts of West Bengal, India through standard WHO protocol. It was observed that, the majority of the tested populations were found to possess resistance to more than one insecticide. In adult bioassay, the toxicity levels of the six tested insecticides was found to decrease in the following order: deltamethrin > lambdacyhalothrin > malathion > propoxur > permethrin > DDT. In larval bioassay, one of the tested populations was found to possess moderate resistance against temephos, mortality percentage 92.5% and 79.8% for WHO (0.0200 ppm) and National Vector Borne disease Programme, India recommended dose (0.0125 ppm) respectively. Carboxylesterases were found to be involved in conferring resistance as revealed in synergistic and quantitative assay against temephos in North Dinajpur (NDP) population and malathion in Alipurduar (APD) and Darjeeling (DAR) populations. Similar correlations were also observed in the majority of the tested populations between reduced susceptibilities against pyrethroid insecticides and Cytochrome P450s activity.
conclusionEfficient disease management in this region can only be achieved through proper integrated vector management along with tools to minimize insecticide resistance. This study may help the concerned authorities in the formulation of an effective vector control strategy throughout this region incorporating the knowledge gained through this study.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.