Evidence map›Paper›PMID 30198843›Full record

ArticleeLife2018

Intrinsic cooperativity potentiates parallel

Trevor R Sorrells, Amanda N Johnson, Conor J Howard, Candace S Britton, Kyle R Fowler, Jordan T Feigerle, P Anthony Weil, Alexander D Johnson

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Evolutionary insights into an ancient fungal transition from land to sea.bioRxiv : the preprint server for biology · 2026
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  9. Ancient transcriptional regulators can easily evolve new pair-wise cooperativity.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Article
  11. Article
  12. A NovelG3 (Bethesda, Md.) · 2020
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Trevor R SorrellsDepartment of Biochemistry and Biophysics, Tetrad Graduate Program, University of California, San Francisco, United States.ORCID http://orcid.org/0000-0002-3527-8622
Amanda N JohnsonDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Conor J HowardDepartment of Biochemistry and Biophysics, Tetrad Graduate Program, University of California, San Francisco, United States.ORCID http://orcid.org/0000-0001-5375-6248
Candace S BrittonDepartment of Biochemistry and Biophysics, Tetrad Graduate Program, University of California, San Francisco, United States.
Kyle R FowlerDepartment of Biochemistry and Biophysics, Tetrad Graduate Program, University of California, San Francisco, United States.
Jordan T FeigerleDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.
P Anthony WeilDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Alexander D JohnsonDepartment of Biochemistry and Biophysics, Tetrad Graduate Program, University of California, San Francisco, United States.
University of California, San Francisco · USVanderbilt University · US

Funding

MECHANISMS OF YEAST TRANSCRIPTIONAL REGULATORSR01GM037049 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSON, ALEXANDER D · 1986 to 2024
$9.4M
TRAINING PROGRAM IN ION CHANNEL AND TRANSPORTER BIOLOGYT32NS007491 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DENTON, JEROD S. · 2001 to 2020
$4.1M
Molecular Mechanism of Gene Transcription ActivationR01GM115892 · NIGMS · VANDERBILT UNIVERSITY · PI NEUERT, GREGOR · 2015 to 2018
$1.2M
NIGMS NIH HHS R01 GM037049NIGMS NIH HHS R01 GM115892NIH HHS GM037049NIH HHS GM115892NINDS NIH HHS T32 NS007491
6 · The paper itself

Abstract

Convergent evolutionary events in independent lineages provide an opportunity to understand why evolution favors certain outcomes over others. We studied such a case where a large set of genes-those coding for the ribosomal proteins-gained

Indexed as

DNA-Binding ProteinsFungal ProteinsGene Expression Regulation, FungalMinichromosome Maintenance 1 ProteinRegulatory Elements, TranscriptionalRibosomal ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsShelterin ComplexTelomere-Binding ProteinsTranscription FactorsDNA-Binding ProteinsFungal ProteinsMCM1 protein, S cerevisiaeMinichromosome Maintenance 1 ProteinRAP1 protein, S cerevisiaeRibosomal ProteinsSaccharomyces cerevisiae ProteinsShelterin ComplexTelomere-Binding ProteinsTranscription Factorschromosomesevolutionevolutionary biologygene expressionKluyveromyces lactisS. cerevisiaetranscription factors

Identifiers

PMID30198843
PMCPMC6173580
OpenAlexW2950061376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.