Evidence map›Paper›PMID 30198382›Full record

ArticleMolecular pain

Activation of the P2X

Pengtao Li, Quan Zhang, Zhi Xiao, Shouyang Yu, Yan Yan, Ying Qin

Open access · goldAbstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. The Central Nervous Mechanism of Stress-Promoting Cancer Progression.International journal of molecular sciences · 2022
    Review
  7. Article
  8. Article
  9. Potentiating Cancer Immune TherapyFrontiers in cell and developmental biology · 2022
    Article
  10. Neurotropin alleviates rat osteocarcinoma pain via PIranian journal of basic medical sciences · 2021
    Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Pengtao Li1 Graduate School, Zunyi Medical University, Zunyi, Guizhou, China.
Quan Zhang2 Key Laboratory of Brain Science, Zunyi Medical University, Zunyi, Guizhou, China.
Zhi Xiao2 Key Laboratory of Brain Science, Zunyi Medical University, Zunyi, Guizhou, China.
Shouyang Yu2 Key Laboratory of Brain Science, Zunyi Medical University, Zunyi, Guizhou, China.
Yan Yan2 Key Laboratory of Brain Science, Zunyi Medical University, Zunyi, Guizhou, China.
Ying Qin3 Research Center for Medicine and Biology, Zunyi Medical University, Zunyi, Guizhou, China.
Zunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Cancer pain is a well-known serious complication in metastatic or terminal cancer patients. Current pain management remains unsatisfactory. The activation of spinal and supraspinal P2X

Indexed as

AcetamidesAnalgesics, OpioidAnimalsBone NeoplasmsCancer PainDisease Models, AnimalDose-Response Relationship, DrugFemaleHyperalgesiaMicroinjectionsPain MeasurementPain ThresholdPeriaqueductal GrayQuinolinesRatsRats, Sprague-DawleyAcetamidesAnalgesics, Opioid(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide)QuinolinesReceptors, Purinergic P2X7Tramadolanalgesic effectBone cancer painmidbrain periaqueductal grayP2X7 receptortramadol

Identifiers

PMID30198382
PMCPMC6176534
OpenAlexW2891492649

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.