Evidence map›Paper›PMID 30198061›Full record

ArticlePharmacoEconomics2018

Multi-Indication Pricing: Nice in Theory but Can it Work in Practice?

Jorge Mestre-Ferrandiz, Néboa Zozaya, Bleric Alcalá, Álvaro Hidalgo-Vega

Abstract read
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In one paragraph

Article in PharmacoEconomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Price determinants and pricing policies concerning potentially innovative health technologies: a scoping review.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Public health policies for the common interest: rethinking EU states' incentives strategies when a pandemic reshuffles all interests.The European journal of health economics : HEPAC : health economics in prevention and care · 2022
    Article
  11. Value-Based Pricing and Budget Impact Analysis for Multi-Indication Drugs: A Case Study of Immunotherapies.International journal of environmental research and public health · 2022
    Article
  12. Review
  13. Pricing Treatments Cost-Effectively when They Have Multiple Indications: Not Just a Simple Threshold Analysis.Medical decision making : an international journal of the Society for Medical Decision Making
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jorge Mestre-FerrandizIndependent Economics Consultant, Madrid, Spain. jormesfer13@gmail.com.ORCID http://orcid.org/0000-0003-0529-1321
Néboa ZozayaWeber Economía y Salud, Majadahonda, Madrid, Spain.ORCID http://orcid.org/0000-0003-4618-6894
Bleric AlcaláWeber Economía y Salud, Majadahonda, Madrid, Spain.ORCID http://orcid.org/0000-0001-8086-1692
Álvaro Hidalgo-VegaFundación Weber, Majadahonda, Madrid, Spain.ORCID http://orcid.org/0000-0003-1031-2051

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For medicines with different valued indications (uses), multi-indication pricing implies charging different prices for different uses. In this article, we assess how multi-indication pricing could help achieve overall strategic objectives of pricing controls, summarise its advantages and disadvantages (vs. uniform pricing) and estimate the hypothetical impact on prices of moving towards multi-indication pricing for specific oncologic medicines in Spain. International experience shows that multi-indication pricing can be implemented in real practice, and indeed a few initiatives are currently in use, albeit mostly applied indirectly through confidential pricing agreements that offer a way to discriminate prices across countries without altering list prices. However, some more sophisticated systems are in place in Italy, and more recently in Spain, where the objective is to monitor usage per patient/indication, and ultimately pay for outcomes. Based on the existing experience, we also outline six conditions required for multi-indication pricing. Multi-indication pricing is a useful tool to determine the relative prices of a drug for multiple (different-valued) indications, but by itself will not offer the 'solution' to what the absolute price should be. That will be driven, among other things, by cost-effectiveness thresholds, if they exist. Overall, we argue multi-indication pricing is nice in theory and it could work in practice, although changes in the manner in which medicines are priced, procured and monitored in clinical practice need to be applied.

Indexed as

CommerceCost-Benefit AnalysisDrug CostsDrug IndustryHumansPharmaceutical PreparationsPharmaceutical Preparations

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.