Evidence map›Paper›PMID 30198026›Full record

ArticleEC orthopaedics2018

Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.

Mark Pitkin

Open access · greenAbstract read
In one paragraph

Article in EC orthopaedics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Mark PitkinProfessor of Physical Medicine and Rehabilitation, Tufts University School of Medicine, Boston, MA, USA.
Tufts University · US

Funding

Tufts Clinical and Translational Research InstituteUL1TR001064 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2013 to 2017
$26.4M
Large animal study on deeply porous transcutaneous pylon for direct skeletal attachmentR44HD090768 · NICHD · POLY-ORTH INTERNATIONAL · PI PITKIN, MARK · 2016 to 2017
$1.4M
Manufacturing technology for skin integrated composite prosthetic pylonR44HD057492 · NICHD · POLY-ORTH INTERNATIONAL · PI PITKIN, MARK · 2009 to 2010
$750k
NCATS NIH HHS UL1 TR001064NICHD NIH HHS R44 HD057492NICHD NIH HHS R44 HD090768
6 · The paper itself

Abstract

backgroundUsing the marrow canal of a tubular bone as a holding compartment for implant stems has been the paradigm in total joint arthroplasty for more than a century, and for direct skeletal attachment of limb prostheses for about forty years. Both interventions rely on the osteogenesis in the inner walls of the marrow canal in a direction radially inwards. It so remains despite the frequent aseptic loosening of the implant stems caused by the resorption of the marrow canal's inner walls which increases the canal's diameter and reduces its capacity to hold the implant. MATERIALS AND

methodsTo improve the bone-device bond, we suggest an implantation methodology that activates positive osteogenic remodeling in the circular direction rather than radially inwards. The rationale is that circular osteogenesis is a component of natural healing of bone fractures and its activating may mitigate the consequences of resorption caused by stress shielding, bone developmental growth and other factors.

resultsCircular osteogenesis occurs in response to the distraction of slots precut into the bone tube. We call this methodology distraction implantation (DI) because of its debt to Ilizarov type distraction osteogenesis (DO). The methodology is accompanied by a design of an implant stem, and has been investigated in a previous pilot animal study.

conclusionDistraction implantation is based on a component of natural healing of bone fractures and therefore has merit to be investigated further.

Indexed as

AnisotropyBone RemodelingDirect Skeletal AttachmentTotal Joint Arthroplasty

Identifiers

PMID30198026
PMCPMC6124505
OpenAlexW2986636259

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.