Evidence map›Paper›PMID 30198015›Full record

ArticleAnnals of eye science2018

Acute retinal arterial ischemia.

Michael Dattilo, Nancy J Newman, Valérie Biousse

Open access · hybridAbstract read
In one paragraph

Article in Annals of eye science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Thrombolysis for Central Retinal Artery Occlusion in 2020: Time Is Vision!Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2020
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Retinal ischemia after cardiovascular interventions: Neuroimaging correlates and timing phenotypes in a consecutive series.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Maculopapillary Bundle Degeneration in Optic Neuropathies.Current neurology and neuroscience reports · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Retinal and optic nerve magnetic resonance diffusion-weighted imaging in acute non-arteritic central retinal artery occlusion.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michael DattiloDepartment of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
Nancy J NewmanDepartment of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
Valérie BiousseDepartment of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
Emory University · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
P30-Core Grant for Vision Research Core CP30EY006360 · NEI · EMORY UNIVERSITY · PI BOATRIGHT, JEFFREY H · 1986 to 2025
$15.3M
VIsion Science Training in AtlantaT32EY007092 · NEI · EMORY UNIVERSITY · PI Machelle T. Pardue · 1985 to 2026
$4.6M
Ocular Fundus Abnormalities for Acute Risk Stratification in TIA and Minor StrokeR01NS089694 · NINDS · EMORY UNIVERSITY · PI NEWMAN, NANCY J · 2014 to 2018
$1.6M
NCATS NIH HHS UL1 TR002378NCRR NIH HHS UL1 RR025008NEI NIH HHS P30 EY006360NEI NIH HHS T32 EY007092NINDS NIH HHS R01 NS089694
6 · The paper itself

Abstract

Acute retinal arterial ischemia, which includes transient monocular vision loss (TMVL), branch retinal artery occlusion (BRAO), central retinal artery occlusion (CRAO) and ophthalmic artery occlusion (OAO), is most commonly the consequence of an embolic phenomenon from the ipsilateral carotid artery, heart or aortic arch, leading to partial or complete occlusion of the central retinal artery (CRA) or its branches. Acute retinal arterial ischemia is the ocular equivalent of acute cerebral ischemia and is an ophthalmic and medical emergency. Patients with acute retinal arterial ischemia are at a high risk of having further vascular events, such as subsequent strokes and myocardial infarctions (MIs). Therefore, prompt diagnosis and urgent referral to appropriate specialists and centers is necessary for further work-up (such as brain magnetic resonance imaging with diffusion weighted imaging, vascular imaging, and cardiac monitoring and imaging) and potential treatment of an urgent etiology (e.g., carotid dissection or critical carotid artery stenosis). Since there are no proven, effective treatments to improve visual outcome following permanent retinal arterial ischemia (central or branch retinal artery occlusion), treatment must focus on secondary prevention measures to decrease the likelihood of subsequent ischemic events.

Indexed as

Central retinal artery occlusion (CRAO)ischemiamanagementstrokethrombolysistreatment

Identifiers

PMID30198015
PMCPMC6124502
OpenAlexW2805507173

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.