Evidence map›Paper›PMID 30197996›Full record

ArticleACS omega2018

Multifunctional Nanosystem for Targeted and Controlled Delivery of Multiple Chemotherapeutic Agents for the Treatment of Drug-Resistant Breast Cancer.

Song Lou, Zongmin Zhao, Micah Dezort, Taylor Lohneis, Chenming Zhang

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Nanomedicine Technologies for Diagnosis and Treatment of Breast Cancer.ACS pharmacology & translational science · 2023
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Song LouDepartment of Biological Systems Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, United States.
Zongmin ZhaoDepartment of Biological Systems Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, United States.
Micah DezortDepartment of Biological Systems Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, United States.
Taylor LohneisDepartment of Biological Systems Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, United States.
Chenming ZhangDepartment of Biological Systems Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, United States.
Virginia Tech · US

Funding

Novel Nanovaccines Against Nicotine AddictionU01DA036850 · NIDA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI ZHANG, CHENMING M · 2014 to 2016
$2.3M
NIDA NIH HHS U01 DA036850
6 · The paper itself

Abstract

By targeting CD44 receptors, inhibiting multidrug resistance (MDR), controlling drug release, and synergistically inhibiting tumor growth, a multilayered nanosystem was developed to serve as a multifunctional platform for the treatment of drug-resistant breast cancers. The multilayer nanosystem is composed of a poly(lactic-

Identifiers

PMID30197996
PMCPMC6120734
OpenAlexW2885295608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.