ArticleTranslational vision science & technology2018
Application of Pattern Recognition Analysis to Optimize Hemifield Asymmetry Patterns for Early Detection of Glaucoma.
Article in Translational vision science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 13 citations in OpenAlex.
- Exploring the relationship between 24-2 visual field and widefield optical coherence tomography data across healthy, glaucoma suspect and glaucoma eyes.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2024Article
- Characterisation of the normal human ganglion cell-inner plexiform layer using widefield optical coherence tomography.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2024Article
- Prediction of visual field defects from macular optical coherence tomography in glaucoma using cluster analysis.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2022Article
- Pointwise and Region-Wise Course of Visual Field Loss in Patients With Glaucoma.Translational vision science & technology · 2022Article
- The Frontloading Fields Study: The Impact of False Positives and Seeding Point Errors on Visual Field Reliability When Using SITA-Faster.Translational vision science & technology · 2022Article
- Modelling normal age-related changes in individual retinal layers using location-specific OCT analysis.Scientific reports · 2021Article
- Cluster analysis reveals patterns of age-related change in anterior chamber depth for gender and ethnicity: clinical implications.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2020Article
- Macula Ganglion Cell Thickness Changes Display Location-Specific Variation Patterns in Intermediate Age-Related Macular Degeneration.Investigative ophthalmology & visual science · 2020Article
- Development of a Spatial Model of Age-Related Change in the Macular Ganglion Cell Layer to Predict Function From Structural Changes.American journal of ophthalmology · 2019Article
- Contrast sensitivity isocontours of the central visual field.Scientific reports · 2019Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess the diagnostic utility of a new hemifield asymmetry analysis derived using pattern recognition contrast sensitivity isocontours (CSIs) within the Humphrey Field Analyzer (HFA) 24-2 visual field (VF) test grid. The performance of an optimal CSI-derived map was compared against a commercially available clustering method (Glaucoma Hemifield Test, GHT).
methodsFive hundred VF results of 116 healthy subjects were used to determine normative distribution limits for comparisons. Pattern recognition analysis was applied to HFA 24-2 sensitivity data to determine CSI theme maps delineating clusters for hemifield comparisons. Then, 1019 VF results from 228 glaucoma patients were assessed using different clustering methods to determine the true-positive rate. We also assessed additional 354 VF results of 145 healthy subjects to determine the false-positive rate.
resultsThe optimum clustering method was the CSI-derived seven-theme class map, which identified more glaucomatous VFs compared with the GHT map. The seven-class theme map also identified more cases compared with the five-, six-, and eight-class maps, suggesting no effect of number of clusters. Integrating information regarding the location of glaucomatous defects to the CSI clusters did not improve detection rate.
conclusionsA clustering map derived using CSIs improved detection of glaucomatous VFs compared with the currently available GHT. An optimized CSI-derived map may serve as an additional means to aid earlier detection of glaucoma. TRANSLATIONAL RELEVANCE: Pattern recognition-derived theme maps provide a means for guiding test point selection for asymmetry analysis in glaucoma assessment.
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