Evidence map›Paper›PMID 30197786›Full record

ArticleEnvironmental science. Nano2017

Synergistic effects of engineered nanoparticles and organics released from laser printers using nano-enabled toners: potential health implications from exposures to the emitted organic aerosol.

Marie-Cecile G Chalbot, Sandra V Pirela, Laura Schifman, Varun Kasaraneni, Vinka Oyanedel-Craver, Dhimiter Bello, Vincent Castranova, Yong Qian, Treye Thomas, Ilias G Kavouras and 1 more

Open access · greenAbstract read
In one paragraph

Article in Environmental science. Nano, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Marie-Cecile G ChalbotDepartment of Environmental Health Sciences, University of Alabama at Birmingham, Birmingham, Alabama.
Sandra V PirelaDepartment of Environmental Health, Center for Nanotechnology and Nanotoxicology, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
Laura SchifmanDepartment of Civil and Environmental Engineering, University of Rhode Island, Kingston, Rhode Island.
Varun KasaraneniDepartment of Civil and Environmental Engineering, University of Rhode Island, Kingston, Rhode Island.
Vinka Oyanedel-CraverDepartment of Civil and Environmental Engineering, University of Rhode Island, Kingston, Rhode Island.
Dhimiter BelloDepartment of Environmental Health, Center for Nanotechnology and Nanotoxicology, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
Vincent CastranovaDepartment of Pharmaceutical Sciences/School of Pharmacy, West Virginia University, Morgantown, West Virginia.
Yong QianPathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia.
Treye ThomasU.S. Consumer Product Safety Commission, Office of Hazard Identification and Reduction, Rockville, Maryland.
Ilias G KavourasDepartment of Environmental Health Sciences, University of Alabama at Birmingham, Birmingham, Alabama.
Philip DemokritouDepartment of Environmental Health, Center for Nanotechnology and Nanotoxicology, T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts.
Harvard University · USUniversity of Rhode Island · USUniversity of Alabama at Birmingham · USHealth Effects Institute · USUnited States Consumer Product Safety Commission · USWest Virginia University · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
Training Program in Molecular and Integrative Physiological SciencesT32HL007118 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LU, QUAN · 1985 to 2025
$14.3M
NanoSight System for Particle Tracking Analysis in Biological FluidsS10OD020086 · OD · HARVARD SCHOOL OF PUBLIC HEALTH · PI LU, QUAN · 2015 to 2015
$144k
NCI NIH HHS P30 CA013148NHLBI NIH HHS T32 HL007118NIH HHS S10 OD020086
6 · The paper itself

Abstract

Recent studies have shown that engineered nanoparticles (ENPs) are incorporated into toner powder used in printing equipment and released during their use. Thus, understanding the functional and structural composition and potential synergistic effects of this complex aerosol and released gaseous co-pollutants is critical in assessing their potential toxicological implications and risks. In this study, toner powder and PEPs were thoroughly examined for functional and molecular composition of the organic fraction and the concentration profile of 16 Environmental Protection Agency (EPA)-priority polycyclic aromatic hydrocarbons (PAH) using state of the art analytical methods. Results show significant differences in abundance of non-exchangeable organic hydrogen of toner powder and PEPs, with a stronger aromatic spectral signature in PEPs. Changes in structural composition of PEPs are indicative of radical additions and free-radical polymerization favored by catalytic reactions, resulting in formation of functionalized organic species. Particularly, accumulation of aromatic carbons with strong styrene-like molecular signatures on PEPs is associated with formation of semivolatile heavier aromatic species (

Identifiers

PMID30197786
PMCPMC6121699
OpenAlexW2750583010

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.