Evidence map›Paper›PMID 30197648›Full record

Trial reportFrontiers in immunology2018

Clonally Expanded Decidual Effector Regulatory T Cells Increase in Late Gestation of Normal Pregnancy, but Not in Preeclampsia, in Humans.

Sayaka Tsuda, Xiaoxin Zhang, Hiroshi Hamana, Tomoko Shima, Akemi Ushijima, Kei Tsuda, Atsushi Muraguchi, Hiroyuki Kishi, Shigeru Saito

Registry-linked trialOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06281262 (The Role of Selected Immunological Indicators and Microbiota in Patients Experiencing Premature Birth and Preeclampsia), which is not on this map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06281262 unknown statusnot on this mapstarted 2023, after this paper: background citation

The Role of Selected Immunological Indicators and Microbiota in Patients Experiencing Premature Birth and Preeclampsia

TypeobservationalSponsorGeneral University Hospital, PragueRan2023 to 2025Enrolled100ConditionsPreterm Birth, PreeclampsiaArmsPeripheral blood collection, Swab sample collection
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Decidual CD4 Effector Memory and Resident Memory T Cells Respond to Cord Blood Allo-Antigens.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Regulatory KIRScience translational medicine · 2025
    Article
  11. Review
  12. Review
  13. Article
  14. Innate Immune Mechanisms in Normal and Adverse Pregnancy.Advances in experimental medicine and biology · 2025
    Review
  15. Review
  16. Article
  17. CD4Frontiers in immunology · 2024
    Article
  18. Review
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sayaka TsudaDepartment of Obstetrics and Gynecology, University of Toyama, Toyama, Japan.
Xiaoxin ZhangDepartment of Obstetrics and Gynecology, University of Toyama, Toyama, Japan.
Hiroshi HamanaDepartment of Innovative Cancer Immunotherapy, Graduate School of Medicine and Pharmaceutical Sciences (Medicine), University of Toyama, Toyama, Japan.
Tomoko ShimaDepartment of Obstetrics and Gynecology, University of Toyama, Toyama, Japan.
Akemi UshijimaDepartment of Obstetrics and Gynecology, University of Toyama, Toyama, Japan.
Kei TsudaDepartment of Obstetrics and Gynecology, University of Toyama, Toyama, Japan.
Atsushi MuraguchiDepartment of Immunology, Graduate School of Medicine and Pharmaceutical Sciences (Medicine), University of Toyama, Toyama, Japan.
Hiroyuki KishiDepartment of Immunology, Graduate School of Medicine and Pharmaceutical Sciences (Medicine), University of Toyama, Toyama, Japan.
Shigeru SaitoDepartment of Obstetrics and Gynecology, University of Toyama, Toyama, Japan.
University of Toyama · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Abortion, SpontaneousAdultDeciduaFemaleHumansPre-EclampsiaPregnancyT-Lymphocytes, Regulatoryeffector regulatory T cellhuman pregnancymiscarriagepreeclampsiaregulatory T cellT cell repertoire

Identifiers

PMID30197648
PMCPMC6118230
OpenAlexW2888457132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.