Evidence map›Paper›PMID 30197578›Full record

ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

The effect of beam shape on physical parameters of head and neck simultaneous-integrated boost intensity-modulated radiation therapy.

Toshiro Tsubouchi, Masashi Yagi, Iori Sumida, Keisuke Tamari, Yuji Seo, Kazuhiko Ogawa

Open access · diamondAbstract read
In one paragraph

Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Toshiro TsubouchiDepartment of Radiation Oncology, Osaka University Graduate School of Medicine, 1, Yamadaoka, Suita-city, Osaka 565-0871, Japan.
Masashi YagiDepartment of Carbon Ion Radiotherapy, Osaka University Graduate School of Medicine, 1, Yamadaoka, Suita-city, Osaka 565-0871, Japan.
Iori SumidaDepartment of Radiation Oncology, Osaka University Graduate School of Medicine, 1, Yamadaoka, Suita-city, Osaka 565-0871, Japan.
Keisuke TamariDepartment of Radiation Oncology, Osaka University Graduate School of Medicine, 1, Yamadaoka, Suita-city, Osaka 565-0871, Japan.
Yuji SeoDepartment of Radiation Oncology, Osaka University Graduate School of Medicine, 1, Yamadaoka, Suita-city, Osaka 565-0871, Japan.
Kazuhiko OgawaDepartment of Radiation Oncology, Osaka University Graduate School of Medicine, 1, Yamadaoka, Suita-city, Osaka 565-0871, Japan.
The University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the influence of the beam shape created by X-rays with "flat beams" and without "flattening-filter-free [FFF] beams" a flattening filter, and the isocenter locations for FFF beams on the treatment of a large irradiated volume for tumours.

backgroundThe increase of dose rate and the decrease of out-of-field dose can be expected for FFF beams and lead to effective and safety radiotherapy. On the other hand, the bell-shaped dose profile is thought to be a factor of negating these advantages. MATERIALS AND

methodsTreatment plans for 15 patients with head and neck cancer were created using XiO (Elekta, Stockholm AB, Sweden) in fixed-gantry step-and-shoot delivery under the same dose constraints. Seven fields of FFF beams with 7 MV and flat beams with 6 MV were used with the technique of intensity-modulated radiation therapy (IMRT). We compared the dose homogeneity and conformity of targets and dose constraints for organs as the plan quality and evaluated physical parameters: monitor unit (MU) values, number of segments and their locations from the isocenter in beam's-eye-view.

resultsNo significant differences were found in the plan quality. The isocenter locations do not affect the physical parameters for FFF beams. It has been confirmed that the number of segments and MU values were 40% higher with FFF beams than with flat beams (

conclusionThis study demonstrates flat dose distribution is more suitable for IMRT with large and complex targets.

Indexed as

Beam profileFlat beamsFlattening-filter-free (FFF) beamsTreatment plans

Identifiers

PMID30197578
PMCPMC6126398
OpenAlexW2889776695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.