Evidence map›Paper›PMID 30197534›Full record

ReviewJournal of pain research2018

Assessment and pathophysiology of pain in cardiac surgery.

Marek Zubrzycki, Andreas Liebold, Christian Skrabal, Helmut Reinelt, Mechthild Ziegler, Ewelina Perdas, Maria Zubrzycka

7 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Journal of pain research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 7 registered trials, which are not on this map. Cited by 77 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 3 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04544254 nacompletednot on this mapstarted 2020, after this paper: background citation

Effectivity of Bilateral Transversus Thoracis Muscle Plane Block to Reduce Pain and Stress Response After Open Heart Surgery: A Study to Interleukin-6 and Cortisol Plasma Concentration, Total Opioid Dose, and Time to First Opioid

TypeinterventionalSponsorIndonesia UniversityRan2020 to 2021Enrolled32ConditionsInterleukin-6, CortisolArmsBilateral transversus thoracis muscle plane block, Control
NCT05054179 phase2 / phase3unknown statusnot on this mapstarted 2022, after this paper: background citation

The Efficacy of Pecto-intercostal Fascial Plane Catheters for Reduction of Sternal Pain in Cardiac Surgery Patients With Complete Median Sternotomy: A Randomized, Placebo-controlled Trial

TypeinterventionalSponsorUniversity of British ColumbiaRan2022 to 2024Enrolled80ConditionsCardiac Surgery, Sternotomy, Acute PainArmsRopivacaine 0.2% Injectable Solution Bolus, Normal Saline Infusion, Ropivacaine 0.2% Injectable Solution Infusion
NCT05534230 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Is Dexmedetomidine Effective at Reducing Pain Scores and Opioid Consumption in Coronary Artery Bypass Grafting (CABG) Patients

TypeinterventionalSponsorWayne State UniversityRan2022 to 2024Enrolled100ConditionsAnalgesiaArmsDexmedetomidine Injectable Solution, Saline
NCT05859061 nacompletednot on this mapstarted 2023, after this paper: background citation

Intraoperative Cryoanalgesia for Pain Management After Sternotomy: A Randomized Pilot Trial

TypeinterventionalSponsorNorthwestern UniversityRan2023 to 2026Enrolled32ConditionsPain, PostoperativeArmscryoICE® system (AtriCure, Inc) with CryoSphere (CryoS) probe
NCT06221150 nacompletednot on this mapstarted 2025, after this paper: background citation

Ultrasound-guided Bilateral Two Levels Serratus Anterior Plane Block in Pediatric Cardiac Surgery With Median Sternotomy : A Randomized Controlled Trial

TypeinterventionalSponsorCairo UniversityRan2025 to 2026Enrolled48ConditionsCongenital Heart DiseaseArmsBilateral two level serratus anterior block
NCT06709625 nacompletednot on this mapstarted 2023, after this paper: background citation

Comparison of the Effects of Erector Spinae Plane Block and Transversus Thoracis Muscle Plane Block on Postoperative Recovery in Patients Undergoing Coronary Artery Surgery

TypeinterventionalSponsorAnkara City Hospital BilkentRan2023 to 2024Enrolled92ConditionsNerve Block, Coronary Artery Bypass, Anesthesia and AnalgesiaArmsTransversus thoracis plane block, Erector spina plane block (ESP)
NCT07768033 nacompletednot on this mapstarted 2026, after this paper: background citation

The effect of chair-assisted yoga practice on sleep quality and pain levels in elderly individuals living in nursing homes

TypeinterventionalSponsorRüveyda BerkRan2026 to 2026Enrolled36ConditionsSleep Quality, PainArmsChair-Supported Yoga
3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 3 syntheses or guidelines pooled it, 206 citations in OpenAlex.

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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Marek ZubrzyckiDepartment of Cardiac Surgery, University of Ulm Medical Center, Ulm, Germany, marek.zubrzycki@uniklinik-ulm.de.
Andreas LieboldDepartment of Cardiac Surgery, University of Ulm Medical Center, Ulm, Germany, marek.zubrzycki@uniklinik-ulm.de.
Christian SkrabalDepartment of Cardiac Surgery, University of Ulm Medical Center, Ulm, Germany, marek.zubrzycki@uniklinik-ulm.de.
Helmut ReineltDepartment of Cardiac Anesthesiology, University of Ulm Medical Center, Ulm, Germany.
Mechthild ZieglerDepartment of Cardiac Anesthesiology, University of Ulm Medical Center, Ulm, Germany.
Ewelina PerdasDepartment of Cardiovascular Physiology, Medical University of Lodz, Lodz, Poland.
Maria ZubrzyckaDepartment of Cardiovascular Physiology, Medical University of Lodz, Lodz, Poland.
Universität Ulm · DEMedical University of Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Analysis of the problem of surgical pain is important in view of the fact that the success of surgical treatment depends largely on proper pain management during the first few days after a cardiosurgical procedure. Postoperative pain is due to intraoperative damage to tissue. It is acute pain of high intensity proportional to the type of procedure. The pain is most intense during the first 24 hours following the surgery and decreases on subsequent days. Its intensity is higher in younger subjects than elderly and obese patients, and preoperative anxiety is also a factor that increases postoperative pain. Ineffective postoperative analgesic therapy may cause several complications that are dangerous to a patient. Inappropriate postoperative pain management may result in chronic pain, immunosuppression, infections, and less effective wound healing. Understanding and better knowledge of physiological disorders and adverse effects resulting from surgical trauma, anesthesia, and extracorporeal circulation, as well as the development of standards for intensive postoperative care units are critical to the improvement of early treatment outcomes and patient comfort.

Indexed as

analgesicscardiac surgerypain intensitypostoperative pain

Identifiers

PMID30197534
PMCPMC6112778
OpenAlexW2888463041

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

and 1 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.