ArticleTherapeutics and clinical risk management2018
Epicardial adipose tissue volume is associated with non-alcoholic fatty liver disease and cardiovascular risk factors in the general population.
Article in Therapeutics and clinical risk management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Meta-Analysis of Non-Alcoholic Fatty Liver Disease and Electromechanical Reconstruction of Myocardium.Archives of Razi Institute · 2022Pooled it
- Evaluating the role of pericoronary adipose tissue on coronary artery disease: insights from CCTA on risk assessment, vascular stenosis, and plaque characteristics.Frontiers in cardiovascular medicine · 2024Article
- Erratum: Addendum and Corrigendum to "Subclinical cardiovascular disease and utility of coronary artery calcium score" [IJC Heart Vasculat. 37 (2021) 100909].International journal of cardiology. Heart & vasculature · 2023Article
- The association of pericardial fat and peri-aortic fat with severity of nonalcoholic fatty liver disease.Scientific reports · 2022Article
- Transient elastography and serum markers of liver fibrosis associate with epicardial adipose tissue and coronary artery calcium in NAFLD.Scientific reports · 2022Observational
- Pericardial fat, thoracic peri-aortic adipose tissue, and systemic inflammatory marker in nonalcoholic fatty liver and abdominal obesity phenotype.Scientific reports · 2022Article
- Development of a Nomogram for Estimating the Risk of Left Ventricular Diastolic Dysfunction in Patients with Non-Alcoholic Fatty Liver Disease.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- The correlation between hepatic fat fraction evaluated by dual-energy computed tomography and high-risk coronary plaques in patients with non-alcoholic fatty liver disease.Japanese journal of radiology · 2021Article
- Association of hepatic steatosis with epicardial fat volume and coronary artery disease in symptomatic patients.La Radiologia medica · 2021Article
- The association between epicardial adipose tissue and non-alcoholic fatty liver disease: A systematic review of existing human studies.EXCLI journal · 2021Review
- Pericardial adipose tissue is an independent risk factor of coronary artery disease and is associated with risk factors of coronary artery disease.The Journal of international medical research · 2020Article
- Nonalcoholic fatty liver disease and cardiovascular disease phenotypes.SAGE open medicine · 2020Review
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpicardial adipose tissue (EAT) is considered an important source of bioactive molecules that can influence coronary arteries directly and is related to the concurrent presence of both obstructive coronary stenosis and myocardial ischemia independently. Non-alcoholic fatty liver disease (NAFLD) has become an emergent health problem worldwide.
aimThis cross-sectional study aimed to address the relationship between the volume of EAT and NAFLD and other cardiovascular risk factors in the general population. MATERIALS AND
methodsIn this study, we selected a total of 2,238 participants aged at least 40 years from the Jidong community in Tangshan, China. The 64-slice CT was used to survey the volume of EAT and liver ultrasonography was used for the diagnosis of NAFLD. The study cohorts were compared according to EAT volume.
resultsCardiovascular risk factors, such as coronary artery calcium score, carotid intima-media thickness, NAFLD, and ideal cardiovascular health metrics were also found to be related to EAT. In multivariate logistic regression analysis, NAFLD groups showed significant association with higher EAT volume, after correcting for main cardiovascular disease risk factors (OR [95% CI], 1.407 [1.117, 1.773]).
conclusionOur findings in a general community population provide evidence that EAT is strongly associated with NAFLD and other cardiovascular risk factors.
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