Evidence map›Paper›PMID 30197509›Full record

ArticleClinical interventions in aging2018

Low bone mineral density is associated with global coronary atherosclerotic plaque burden in stable angina patients.

Xue-Qiang Guan, Yang-Jing Xue, Jie Wang, Jun Ma, Yue-Chun Li, Cheng Zheng, Sai-Zhu Wu

Open access · goldAbstract read
In one paragraph

Article in Clinical interventions in aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  7. Low bone mineral density and coronary artery disease: A systematic review and meta-analysis.International journal of cardiology. Heart & vasculature · 2021
    Review
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  10. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xue-Qiang GuanDepartment of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China, wusaizhu_nfdx@163.com.
Yang-Jing XueDepartment of Cardiology, Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Jie WangDepartment of Cardiology, Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Jun MaDepartment of Cardiology, Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Yue-Chun LiDepartment of Cardiology, Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Cheng ZhengDepartment of Cardiology, Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Sai-Zhu WuDepartment of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China, wusaizhu_nfdx@163.com.
Wenzhou Medical University · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccelerated atherosclerosis is considered to be the linking factor between low bone mineral density (BMD) and increased cardiovascular events and mortality, while some coronary angiographic studies do not support this point. In this study, we attempt to provide a distinct comprehensive view of the relationship between BMD and the angiographically determined coronary atherosclerotic burden.

methodsA total of 459 consecutive patients with stable chest pain suspected of coronary artery disease (CAD) underwent both dual-energy X-ray absorptiometry scan and selective coronary angiography. The association between BMD and global coronary atherosclerotic plaque burden as represented by the multivessel involvement and the modified Gensini score was analyzed.

resultsMultivariable analysis revealed that the low BMD at femoral neck and total hip was an independent correlate of multivessel CAD. The

conclusionThis cross-sectional study elucidated an inverse relationship between hip BMD and the modified Gensini score, and low hip BMD values (

Indexed as

Absorptiometry, PhotonAgedBone DensityCoronary AngiographyCoronary Artery DiseaseCross-Sectional StudiesFemaleFemur NeckHipHumansMaleMiddle AgedPlaque, Atheroscleroticbone mineral densitycoronary artery diseaseglobal coronary atherosclerotic plaque burdenmodified Gensini score

Identifiers

PMID30197509
PMCPMC6112784
OpenAlexW2888235264

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.