Evidence map›Paper›PMID 30197412›Full record

ArticleThe American journal of case reports2018

A Case of Ocular Kaposi's Sarcoma Successfully Treated with Highly Active Antiretroviral Therapy (HAART) Combined with Docetaxel.

Chongfei Jin, Hamza Minhas, Amandeep Kaur, Sreenath Kodali, Vladimir Gotlieb

Abstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. A rare case of bilateral conjunctival Kaposi's sarcoma in a HIV-negative patient.American journal of ophthalmology case reports · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chongfei JinDepartment of Medicine, Brookdale University Hospital and Medical Center, Brooklyn, NY, USA.
Hamza MinhasDivision of Hematology and Oncology, Brookdale University Hospital and Medical Center, Brooklyn, NY, USA.
Amandeep KaurDepartment of Medicine, Brookdale University Hospital and Medical Center, Brooklyn, NY, USA.
Sreenath KodaliDivision of Hematology and Oncology, Brookdale University Hospital and Medical Center, Brooklyn, NY, USA.
Vladimir GotliebDivision of Hematology and Oncology, Brookdale University Hospital and Medical Center, Brooklyn, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Ocular Kaposi's sarcoma (KS) involving the conjunctiva and ocular adnexa is uncommon and is usually treated with cryotherapy or surgical excision. We report a case of ocular KS successfully treated with HAART combined with 8 cycles of weekly docetaxel. CASE REPORT Our patient was a 24-year-old, treatment-naïve, HIV-positive (CD4 cell count 198 cells/mm3), homosexual man treated as having atypical hordeolum and subconjunctival hemorrhage, and later confirmed with pathology to have ocular KS with immunohistochemistry study showing KS with positive HHV8, CD34, CD31, and focal positive staining with Factor VIIIRA. HAART therapy was initiated combined with weekly docetaxel. With 2-month treatment of HAART and 8 cycles of weekly docetaxel, the KS of the bulbar conjunctiva and the eyelid partially resolved. CONCLUSIONS HAART combined with weekly docetaxel is an effective and well-tolerated option for ocular KS, which could be considered before cryotherapy or surgical excision.

Indexed as

Antineoplastic AgentsAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveDocetaxelEye NeoplasmsGingival NeoplasmsHIV InfectionsHumansMaleSarcoma, KaposiYoung AdultAntineoplastic AgentsAnti-Retroviral AgentsDocetaxel

Identifiers

PMID30197412
PMCPMC6140454

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.