Evidence map›Paper›PMID 30196680›Full record

ArticleNeurointervention2018

Contact Aspiration versus Stent-Retriever Thrombectomy for Distal Middle Cerebral Artery Occlusions in Acute Ischemic Stroke: Meta-Analysis.

Kevin Phan, Julian Maingard, Hong Kuan Kok, Adam A Dmytriw, Sourabh Goyal, Ronil Chandra, Duncan Mark Brooks, Vincent Thijs, Hamed Asadi

Open access · diamondAbstract read
In one paragraph

Article in Neurointervention, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. The effect of occlusion location and technique in mechanical thrombectomy for minor stroke.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  5. Observational
  6. Observational
  7. Article
  8. Article
  9. Article
  10. A multicenter, propensity score-matched analysis of functional outcomes and recanalization success with or without Trevo for Medium and distal vessel occlusion.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Prediction of mTICI 3 recanalization and clinical outcomes in endovascular thrombectomy for acute ischemic stroke: a retrospective study in the Taiwan registry.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Article
  16. Article
  17. ADAPT technique in ischemic stroke treatment of M2 middle cerebral artery occlusions in comparison to M1 occlusions: Post hoc analysis of the PROMISE study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2020
    Article
  18. Review
  19. Endovascular Treatment of Acute Ischemic Stroke.Current treatment options in cardiovascular medicine · 2019
    Review
  20. Contact Aspiration Alone or Combined With Stent Retriever Thrombectomy for Middle Cerebral Artery Large Vessel Occlusion.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Kevin PhanNeuroSpine Surgery Research Group, Prince of Wales Private Hospital, Randwick, Australia.
Julian MaingardInterventional Neuroradiology Service, Department of Radiology, Austin Hospital, Heidelberg, Australia.
Hong Kuan KokDepartment of Interventional Radiology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Adam A DmytriwDepartment of Radiology, University of Toronto, Toronto, Canada.
Sourabh GoyalNeuroSpine Surgery Research Group, Prince of Wales Private Hospital, Randwick, Australia.
Ronil ChandraInterventional Neuroradiology Unit, Monash Imaging, Monash Health, Clayton, Australia.
Duncan Mark BrooksInterventional Neuroradiology Service, Department of Radiology, Austin Hospital, Heidelberg, Australia.
Vincent ThijsStroke Division, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Australia.
Hamed AsadiInterventional Neuroradiology Service, Department of Radiology, Austin Hospital, Heidelberg, Australia.
Deakin University · AUMonash Health · AUPrince of Wales Hospital · AUGuy's and St Thomas' NHS Foundation Trust · GBUniversity of Melbourne · AUUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe evidence for endovascular therapy and choice of technique in distal middle cerebral artery (MCA) M2 segment occlusions in acute ischemic stroke remains controversial. We aimed to conduct a systematic review and meta-analysis primarily comparing reperfusion rates of stent-retrieval versus contact aspiration for M2 occlusions. MATERIALS AND

methodsStudy selection included cohorts of patients with distal MCA occlusions in acute ischemic strokes treated with an endovascular approach including stent-retrieval or contact aspiration. Twelve studies were selected for meta-analysis for a total of 835 cases. Meta-analysis by proportions was conducted on parameters including baseline and procedural characteristics, thrombolysis in cerebral infarction (TICI) 2b-3 outcomes, and 90-day modified Rankin scale (mRS) outcomes.

resultsHypertension and hyperlipidemia were more prevalent in stent-retriever patients. Pooled baseline National Institute of Health Stroke Scale scores and Alberta Stroke Program Early Computed Tomography Score imaging scores were similar. Pooled time onset of symptoms to door arrival was higher for the stent-retrieval group (154 vs. 97.4 minutes, P=0.01), as was time to groin puncture (259.9 vs. 156.2 minutes, P=0.02), but there was no difference in procedure time. The TICI 2b-3 recanalization rate was similar (80.5% vs. 86.8%, P=0.168). The frequency of mRS 0-2 at 90-day was also similar (74.5% vs. 59.9%, P=0.120), and an excellent mRS 0-1 was lower for stent-retrievers (39.9% vs. 65.6%, P=0.003). A significant negative correlation was found between onset to groin puncture time and the proportion of patients with a good mRS (r=-0.71, P=0.048).

conclusionBoth endovascular techniques achieved recanalization rates greater than 80% and 90-day outcomes of minimal disability with similar complication rates. The literature is skewed by aspiration cases being performed sooner after onset of stroke compared to stent-retriever cases.

Indexed as

Cerebrovascular disordersEndovascular proceduresIschemiaMiddle cerebral arteryStrokeThrombectomy

Identifiers

PMID30196680
PMCPMC6132031
OpenAlexW2890406495

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.