Evidence map›Paper›PMID 30196522›Full record

ArticleLa Radiologia medica2019

Cervical lymphadenopathy: can the histogram analysis of apparent diffusion coefficient help to differentiate between lymphoma and squamous cell carcinoma in patients with unknown clinical primary tumor?

Antonello Vidiri, Silvia Minosse, Francesca Piludu, Raul Pellini, Giovanni Cristalli, Ramy Kayal, Giorgio Carlino, Daniela Renzi, Renato Covello, Simona Marzi

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In one paragraph

Article in La Radiologia medica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  4. Article
  5. Review
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Antonello VidiriRadiology and Diagnostic Imaging Department, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy. antonello.vidiri@ifo.gov.it.ORCID http://orcid.org/0000-0001-6203-4642
Silvia MinosseMedical Physics Laboratory, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
Francesca PiluduDepartment of Radiology, F. Policlinico Gemelli - IRCCS, Largo Agostino Gemelli 8, 00168, Rome, Italy.
Raul PelliniDepartment of Otolaryngology and Head and Neck Surgery, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
Giovanni CristalliDepartment of Otolaryngology and Head and Neck Surgery, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
Ramy KayalRadiology and Diagnostic Imaging Department, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
Giorgio CarlinoDepartment of Radiology, F. Policlinico Gemelli - IRCCS, Largo Agostino Gemelli 8, 00168, Rome, Italy.
Daniela RenziDepartment of Hematology, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
Renato CovelloDepartment of Pathology, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
Simona MarziMedical Physics Laboratory, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITAgostino Gemelli University Polyclinic · ITDeutsches Historisches Institut Rom · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo retrospectively evaluate the value of whole-lesion histogram analysis of apparent diffusion coefficient (ADC) maps in differentiating between lymphoma and metastatic squamous cell carcinoma (SCC) of unknown clinical primary in neck nodes.

methodsA total of 39 patients, 20 affected by lymphoma and 19 affected by metastatic non-nasopharyngeal SCC, were included in this retrospective study. All patients underwent MR imaging with a 1.5 T scanner system, including diffusion-weighted imaging (DWI) with three different b values (b = 0, 500 and 800 s/mm

resultsThe SCCs showed significantly higher median ADC (ADC

conclusionsThe whole-lesion ADC histogram analysis of cervical lymphadenopathy may help to discriminate lymphomas from non-nasopharyngeal SCC in patients with unknown clinical primary tumor.

Indexed as

AdolescentAdultAgedAged, 80 and overDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingFemaleHumansImage Interpretation, Computer-AssistedLymphadenopathyLymphomaMaleMiddle AgedNeoplasms, Unknown PrimaryRetrospective StudiesSquamous Cell Carcinoma of Head and NeckDiffusion-weighted imagingHead and neck cancerNeck nodesQuantitative imaging

Identifiers

PMID30196522
OpenAlexW2889821912

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.