Evidence map›Paper›PMID 30196449›Full record

ReviewEuropean journal of applied physiology2019

Exploring the effect of exercise training on testicular function.

Bárbara Matos, John Howl, Rita Ferreira, Margarida Fardilha

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in European journal of applied physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 6 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 6 syntheses or guidelines pooled it, 41 citations in OpenAlex.

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  17. Physical activity and sperm quality: influence in sperm donors.Reproductive biology and endocrinology : RB&E · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Bárbara MatosQOPNA, Department of Chemistry, University of Aveiro, 3810-193, Aveiro, Portugal.
John HowlMolecular Pharmacology Group, Research Institute in Healthcare Science, University of Wolverhampton, Wolverhampton, WV1 1LY, UK.
Rita FerreiraQOPNA, Department of Chemistry, University of Aveiro, 3810-193, Aveiro, Portugal.
Margarida FardilhaSignal Transduction Laboratory, iBiMED, Department of Medical Sciences, University of Aveiro, 3810-193, Aveiro, Portugal. mfardilha@ua.pt.
University of Aveiro · PTUniversity of Wolverhampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe impact of exercise training on testicular function is relatively ill-defined. To gain new insights into this important topic, published data, deriving from both humans and animal studies, were critically analyzed. RESULTS AND

conclusionsThe effects of exercise on the hypothalamus-pituitary-gonadal axis, influenced by the type, intensity and duration of the exercise program, can be evaluated in terms of total and free testosterone and/or luteinizing hormone and follicle-stimulating hormone serum levels and sperm parameters. High-intensity exercise promotes a common decrease in these parameters, and therefore, negatively impacts upon testicular function. However, published data for moderate-intensity exercise training are inconsistent. Conversely, there is consistent evidence to support the benefits of exercise training to prevent and/or counteract the impairment of testis function caused by aging, obesity and doxorubicin treatment. This positive effect is likely the consequence of decreased oxidative stress and inflammatory status. In the future, it will be important to clarify the molecular mechanisms which explain these reported discrepancies and to establish guidelines for an active lifestyle to promote healthy testicular function.

Indexed as

ExerciseHumansHypothalamo-Hypophyseal SystemMaleTestisTestosteroneTestosteroneAgingHypothalamus–pituitary–gonadal axisObesityPhysical activityTestosterone

Identifiers

PMID30196449
OpenAlexW2890849484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.