Evidence map›Paper›PMID 30196422›Full record

ArticleAnalytical and bioanalytical chemistry2018

Magnetic carbon nanocomposites as a MALDI co-matrix enhancing MS-based glycomics.

Alireza Banazadeh, Seth Williamson, Masoud Zabet, Ahmed Hussien, Yehia Mechref

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Alireza BanazadehDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, 79409, USA.
Seth WilliamsonDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, 79409, USA.
Masoud ZabetCenter for Biotechnology and Genomics, Texas Tech University, Lubbock, TX, 79409, USA.
Ahmed HussienDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, 79409, USA.
Yehia MechrefDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX, 79409, USA. yehia.mechref@ttu.edu.
Texas Tech University · US

Funding

Sensitive and Quantitative MS-bases Glycomic Mapping PlatformR01GM112490 · NIGMS · TEXAS TECH UNIVERSITY · PI MECHREF, YEHIA · 2014 to 2024
$3.2M
Quantitative Characterization of Glycopeptide IsomersR01GM130091 · NIGMS · TEXAS TECH UNIVERSITY · PI Yehia Mechref · 2019 to 2026
$2.5M
NIGMS NIH HHS 1R01GM112490-04NIGMS NIH HHS R01 GM112490NIGMS NIH HHS R01 GM130091
6 · The paper itself

Abstract

More than 50% of all known proteins are glycosylated, which is critical for many biological processes such as protein folding and signal transduction. Glycosylation has proven to be associated with different mammalian diseases such as breast and liver cancers. Therefore, characterization of glycans is highly important to facilitate a better understanding of the development and progression of many human diseases. Although matrix-assisted laser desorption ionization-mass spectrometry (MALDI-MS) offers several advantages such as ease of operation and short analysis times, however, due to the complexity of glycan structures and their low ionization efficiency, there are still challenges that need to be addressed to achieve sensitive glycan analysis. Here, magnetic carbon nanocomposites (CNPs@Fe

Indexed as

CarbonFerrous CompoundsGlycomicsMagneticsMetal NanoparticlesSensitivity and SpecificitySpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationCarbonFerrous Compoundsferrous oxideGlycomicsHuman blood serumIn-source decay fragmentationMagnetic carbon nanoparticlesMALDI

Identifiers

PMID30196422
PMCPMC6375713
OpenAlexW2889668811

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.