Evidence map›Paper›PMID 30196373›Full record

Observational studyNeuroradiology2018

"Hyperdense artery sign" in early ischemic stroke: diagnostic value of model-based reconstruction approach in comparison with standard hybrid iterative reconstruction algorithm.

Sophie Lombardi, Luca Riva, Mirko Patassini, Paolo Remida, Cristina Capraro, Francesco Canonico, Cammillo Talei Franzesi, Davide Ippolito

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sophie LombardiDepartment of Diagnostic Radiology, "San Gerardo" Hospital, Via Pergolesi 33, 20900, Monza, MB, Italy. sophielombardi@mac.com.ORCID http://orcid.org/0000-0003-1050-3640
Luca RivaDepartment of Diagnostic Radiology, "San Gerardo" Hospital, Via Pergolesi 33, 20900, Monza, MB, Italy.
Mirko PatassiniDepartment of Diagnostic Radiology, "San Gerardo" Hospital, Via Pergolesi 33, 20900, Monza, MB, Italy.
Paolo RemidaDepartment of Diagnostic Radiology, "San Gerardo" Hospital, Via Pergolesi 33, 20900, Monza, MB, Italy.
Cristina CapraroDepartment of Diagnostic Radiology, "San Gerardo" Hospital, Via Pergolesi 33, 20900, Monza, MB, Italy.
Francesco CanonicoDepartment of Diagnostic Radiology, "San Gerardo" Hospital, Via Pergolesi 33, 20900, Monza, MB, Italy.
Cammillo Talei FranzesiDepartment of Diagnostic Radiology, "San Gerardo" Hospital, Via Pergolesi 33, 20900, Monza, MB, Italy.
Davide IppolitoDepartment of Diagnostic Radiology, "San Gerardo" Hospital, Via Pergolesi 33, 20900, Monza, MB, Italy.
Azienda Ospedaliera San Gerardo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHyperdense artery sign is the earliest sign of ischemic stroke on non-enhanced computed tomography and it can be visible long before parenchymal changes. The aim of our study was to compare diagnostic value of model-based iterative reconstruction algorithm (IMR) with that of iterative reconstruction algorithm (iDose4) in identifying hyperdense artery sign.

methodsWe selected 56 consecutive patients suspected for ischemic stroke, who underwent a NCCT and that demonstrated a vessel occlusion at angio-CT or developed ischemic lesion at follow-up CT. Two readers randomly analyzed images of NCCT reconstructed both with iDose4 (4 mm) and IMR (2 mm), reporting presence of hyperdense artery sign (0: no; 1: yes; 2: not sure). They rated image quality on a 4-point scale (1: unacceptable; 4: more than average) and recorded HU values of clot and of normal vessel and measured noise index, CNR and SNR.

resultsMean values of CTDI, DLP, and ED were respectively of 43 mGy, 819.7 mGy cm, and 1.72 mSv. By analyzing the IMR reconstruction, both readers were able to recognize hyperdense vessel sign in 55/56 patients, while only in 12/56 patients were identified with iDose. IMR obtained better rating of image quality (mean score for IMR 3.32 vs 2.53 for iDose), higher clot density (57.2 vs 46.7 HU), lower noise index (5 vs 2), higher CNR and SNR (respectively 4.2 vs 2 and 16.8 vs 8.5).

conclusionsModel-based approach significantly increases sensitivity in detecting hyperdense artery sign, offering higher SNR and CNR in brain CT images in comparison with standard hybrid reconstruction algorithm.

Indexed as

AlgorithmsBrain IschemiaCerebral AngiographyComputed Tomography AngiographyDiagnosis, DifferentialHumansRadiation DosageRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesSensitivity and SpecificitySignal-To-Noise RatioStrokeTomography, X-Ray ComputedBrain CTBrain strokeComputed tomographyHyperdense artery signIterative reconstruction algorithm

Identifiers

PMID30196373
OpenAlexW2892364559

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.