Evidence map›Paper›PMID 30196272›Full record

ArticleThe British journal of ophthalmology2019

Active cytomegalovirus retinitis after the start of antiretroviral therapy.

David Heiden, NiNi Tun, Frank N Smithuis, Jeremy David Keenan, Catherine E Oldenburg, Gary N Holland, W Lawrence Drew

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The British journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Observational
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

David HeidenDepartment of Ophthalmology, California Pacific Medical Center, Pacific Eye Associates, San Francisco, USA davidheiden@gmail.com.
NiNi TunMedical Action Myanmar, Yangon, Myanmar.
Frank N SmithuisMyanmar Oxford Clinical Research Unit and Medical Action Myanmar, Yangon, Myanmar.
Jeremy David KeenanFrancis I. Proctor Foundation, University of California, San Francisco, San Francisco, USA.ORCID 0000-0002-7118-1457
Catherine E OldenburgFrancis I. Proctor Foundation, University of California, San Francisco, San Francisco, USA.
Gary N HollandDepartment of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, USA.
W Lawrence DrewDepartments of Laboratory Medicine, UCSF and Mount Zion Medical Center, San Francisco, USA.

Funding

The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

Patients with AIDS-related cytomegalovirus (CMV) retinitis receiving combined antiretroviral therapy (cART), but not specific anti-CMV therapy, consistently showed active retinitis for several months. Delayed diagnosis and treatment of CMV retinitis may have severe consequences. Patients first entering care with advanced HIV infection and vulnerability to reactivation of latent CMV infection should be screened immediately for CMV retinitis by dilated indirect ophthalmoscopy and treated with specific anti-CMV therapy without delay, in addition to cART.

Indexed as

AdultAIDS-Related Opportunistic InfectionsAntiretroviral Therapy, Highly ActiveAntiviral AgentsCD4 Lymphocyte CountCD4-Positive T-LymphocytesCross-Sectional StudiesCytomegalovirus RetinitisFemaleHumansMaleOphthalmoscopyRetrospective StudiesVisual AcuityAntiviral AgentsAIDS-related opportunistic infectionsCMV retinitiscytomegalovirusdiagnosis CMV retinitiseye examination in AIDStreatment CMV retinitis

Identifiers

PMID30196272
PMCPMC9982650

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.