Evidence map›Paper›PMID 30195936›Full record

ArticleBiophysical journal2018

Computational Investigation of Ripple Dynamics in Biofilms in Flowing Systems.

Nicholas G Cogan, Jian Li, Stefania Fabbri, Paul Stoodley

Abstract read
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Bayesian estimation ofBiofilm · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nicholas G CoganDepartment of Mathematics, Florida State University, Tallahassee, Florida. Electronic address: ncogan@fsu.edu.
Jian LiDepartment of Mathematics, Florida State University, Tallahassee, Florida.
Stefania FabbriNational Center for Advanced Tribology at Southampton, Department of Mechanical Engineering, University of Southampton, Southampton, UK.
Paul StoodleyNational Center for Advanced Tribology at Southampton, Department of Mechanical Engineering, University of Southampton, Southampton, UK; Department of Microbial Infection and Immunity, Ohio State University, Columbus, Ohio.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofilms are collections of microorganisms that aggregate using a self-produced matrix of extracellular polymeric substance. It has been broadly demonstrated that many microbial infections in the body, including dental plaque, involve biofilms. While studying experimental models of biofilms relevant to mechanical removal of oral biofilms, distinct ripple patterns have been observed. In this work, we describe a multiphase model used to approximate the dynamics of the biofilm removal process. We show that the fully nonlinear model provides a better representation of the experimental data than the linear stability analysis. In particular, we show that the full model more accurately reflects the relationship between the apparent wavelength and the external forcing velocities, especially at mid-to-low velocities at which the linear theory neglects important interactions. Finally, the model provides a framework by which the removal process (presumably governed by highly nonlinear behavior) can be studied.

Indexed as

BiofilmsMechanical PhenomenaModels, BiologicalKineticsNonlinear Dynamics

Identifiers

PMID30195936
PMCPMC6170598

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.