ArticleAmerican journal of ophthalmology2018
Racial Differences in Rate of Change of Spectral-Domain Optical Coherence Tomography-Measured Minimum Rim Width and Retinal Nerve Fiber Layer Thickness.
Article in American journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 34 citations in OpenAlex.
- Association Between Optic Nerve Head Prelaminar Schisis and Visual Field Progression in Glaucoma.American journal of ophthalmology · 2025Article
- Interpretable Machine Learning Predictions of Bruch's Membrane Opening-Minimum Rim Width Using Retinal Nerve Fiber Layer Values and Visual Field Global Indexes.Bioengineering (Basel, Switzerland) · 2025Article
- Racial-ethnic disparities in concurrent rates of peripapillary & macular OCT parameters among a large glaucomatous clinical population.Eye (London, England) · 2024Article
- Long-term variability of retinal nerve fibre layer thickness measurement in patients with glaucoma of African and European descents.The British journal of ophthalmology · 2024Article
- Time to Glaucoma Progression Detection by Optical Coherence Tomography in Individuals of African and European Descents.American journal of ophthalmology · 2024Article
- Aging-associated changes of optical coherence tomography-measured ganglion cell-related retinal layer thickness and visual sensitivity in normal Japanese.Japanese journal of ophthalmology · 2024Observational
- Longitudinal Rates of Change in Structural Parameters of Optical Coherence Tomography in Primary Angle Closure Glaucoma following Laser Iridotomy along with Peripheral Iridoplasty.Journal of ophthalmology · 2024Article
- Clinical Factors Associated With Long-Term OCT Variability in Glaucoma.American journal of ophthalmology · 2023Article
- Comparison of Ganglion Cell Layer and Inner Plexiform Layer Rates of Change in Suspected and Established Glaucoma.American journal of ophthalmology · 2023Article
- Focused analysis of RNFL decay in glaucomatous eyes using circular statistics on high-resolution OCT data.PloS one · 2023Article
- Disparities in Vision Health and Eye Care.Ophthalmology · 2022Article
- Comparison of retinal nerve fiber layer thickness and Bruch's membrane opening minimum rim width thinning rate in open-angle glaucoma.Scientific reports · 2022Article
- Bruch Membrane Opening Detection Accuracy in Healthy Eyes and Eyes With Glaucoma With and Without Axial High Myopia in an American and Korean Cohort.American journal of ophthalmology · 2022Article
- Disc Hemorrhages Are Associated With Localized Three-Dimensional Neuroretinal Rim Thickness Progression in Open-Angle Glaucoma.American journal of ophthalmology · 2022Article
- Article
- Circular functional analysis of OCT data for precise identification of structural phenotypes in the eye.Scientific reports · 2021Article
- The Effect of Age on Increasing Susceptibility to Retinal Nerve Fiber Layer Loss in Glaucoma.Investigative ophthalmology & visual science · 2020Article
- Rate of Change in Bruch's Membrane Opening-Minimum Rim Width and Peripapillary RNFL in Early Normal Tension Glaucoma.Journal of clinical medicine · 2020Article
- Analysis of Neuroretinal Rim by Age, Race, and Sex Using High-Density 3-Dimensional Spectral-Domain Optical Coherence Tomography.Journal of glaucoma · 2019Article
- Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria.Journal of current glaucoma practiceArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
purposeTo compare race-related differences in estimated rate of change of Bruch's membrane opening-minimum rim width (BMO-MRW) and circumpapillary retinal nerve fiber layer thickness (RNFLT) in healthy, glaucoma suspect, and glaucoma eyes of individuals of European (ED) and African descent (AD).
designProspective cohort study.
methodsThis study investigated rate of change of BMO-MRW and RNFLT in 124 healthy, 227 glaucoma suspect, and 177 glaucoma eyes followed for approximately 3 years and tested with optical coherence tomography every 6 months. Suspect eyes had a history of untreated intraocular pressure (IOP) ≥ 22 mm Hg or suspicion of glaucoma by optic disc photograph assessment without repeatable abnormal standard automated perimetry (SAP) results. Glaucoma eyes had repeatable abnormal SAP results (GHT ONL or PSD ≤ 5%). Mixed-effects models were used to estimate the rate of change after controlling for age, mean follow-up IOP, central corneal thickness, axial length, and BMO area.
resultsA race-related difference in rate of change of global BMO-MRW but not average RNFLT in suspect eyes was observed. Rate of change of BMO-MRW was -1.82 μm/year and -2.20 μm/year in ED and AD suspect eyes, respectively (P = .03). Rate of change of RNFLT was -0.64 μm/year and -0.75 μm/year in ED and AD suspect eyes, respectively (P = .75). No race-related differences in change rate were found in healthy or glaucoma eyes.
conclusionRace is an important consideration when assessing structural change, particularly minimum rim width, in glaucoma suspect eyes. Differences in rate of structural change may help explain racial disparities in glaucoma susceptibility.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.