Evidence map›Paper›PMID 30195656›Full record

ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2018

Assessment of mammographic breast density after sleeve gastrectomy.

Rafael Alvarez, Elika Ridelman, Natalie Rizk, Morgan S White, Chuan Zhou, Heang-Ping Chan, Oliver A Varban, Mark A Helvie, Randy J Seeley

Open access · greenAbstract read
In one paragraph

Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rafael AlvarezDepartment of Surgery, University of Michigan, Ann Arbor, Michigan. Electronic address: rafalv@med.umich.edu.
Elika RidelmanDepartment of Surgery, University of Michigan, Ann Arbor, Michigan.
Natalie RizkDepartment of Surgery, University of Michigan, Ann Arbor, Michigan.
Morgan S WhiteMedical School, University of Michigan, Ann Arbor, Michigan.
Chuan ZhouDepartment of Radiology, University of Michigan, Ann Arbor, Michigan.
Heang-Ping ChanDepartment of Radiology, University of Michigan, Ann Arbor, Michigan.
Oliver A VarbanDepartment of Surgery, University of Michigan, Ann Arbor, Michigan.
Mark A HelvieDepartment of Radiology, University of Michigan, Ann Arbor, Michigan.
Randy J SeeleyDepartment of Surgery, University of Michigan, Ann Arbor, Michigan.
University of Michigan · US

Funding

Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Kanakadurga Singer · 2010 to 2026
$20.3M
Obesity Surgery Scientist Training ProgramT32DK108740 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin Brigham Dimick, RANDY J SEELEY · 2016 to 2026
$2.2M
Molecular mechanism for bariatric surgery on obesity and diabetesR01DK107652 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEELEY, RANDY J · 2016 to 2018
$1.4M
NIDDK NIH HHS P30 DK089503NIDDK NIH HHS R01 DK107652NIDDK NIH HHS T32 DK108740
6 · The paper itself

Abstract

backgroundMammographic breast density (BD) is an independent risk factor for breast cancer. The effects of bariatric surgery on BD are unknown.

objectivesTo investigate BD changes after sleeve gastrectomy (SG).

settingUniversity hospital, United States.

methodsFifty women with mammograms before and after SG performed from 2009 to 2015 were identified after excluding patients with a history of breast cancer, hormone replacement, and/or breast surgery. Patient age, menopausal status, co-morbidities, hemoglobin A1C, and body mass index were collected. Craniocaudal mammographic views before and after SG were interpreted by a blinded radiologist and analyzed by software to obtain breast imaging reporting and data system density categories, breast area, BD, and absolute dense breast area (ADA). Analyses were performed using χ

resultsRadiologist interpretation revealed a significant increase in breast imaging reporting and data system B+C category (68% versus 54%; P = .0095) and BD (9.8 ± 7.4% versus 8.3 ± 6.4%; P = .0006) after SG. Software analyses showed a postoperative decrease in breast area (75,398.9 ± 22,941.2 versus 90,655.9 ± 25,621.0 pixels; P < .0001) and ADA (7287.1 ± 3951.3 versus 8204.6 ± 4769.9 pixels; P = .0314) with no significant change in BD. Reduction in ADA was accentuated in postmenopausal patients. Declining breast area was directly correlated with body mass index reduction (R

conclusionsADA decreases after SG, particularly in postmenopausal patients. Software-generated ADA may be more accurate than radiologist-estimated BD or breast imaging reporting and data system for capturing changes in dense breast tissue after SG.

Indexed as

GastrectomyMammographyAdultBody Mass IndexBreast DensityFemaleHumansMenopauseMiddle AgedObesity, MorbidRetrospective StudiesWeight LossBariatric surgeryBreast cancerBreast cancer riskBreast densityDense breast tissueDiabetesGlucose metabolismMammographic breast densityMammographyMenopausal statusMetabolic surgeryPostmenopausalPremenopausalSleeve gastrectomyWeight loss surgery

Identifiers

PMID30195656
PMCPMC6289637
OpenAlexW2887507945

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.