SynthesisLancet (London, England)2018
Mortality due to low-quality health systems in the universal health coverage era: a systematic analysis of amenable deaths in 137 countries.
Synthesis in Lancet (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 524 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
524 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- Leadership practices and maternal and child health outcomes in Sub-Saharan Africa: a systematic review.BMC health services research · 2026Pooled it
- Barriers and facilitators to integrating non-communicable disease care within primary healthcare systems in low-resource countries: a systematic review.BMC health services research · 2026Pooled it
- A systematic review and meta-analysis of healthcare service quality in Iran using the SERVQUAL model: a comparison before and after the Health Transformation Plan.BMC health services research · 2026Pooled it
- Quality of neonatal intensive care in Africa: a systematic review and meta-analysis.BMC health services research · 2026Pooled it
- Facilitators and barriers to the implementation of maternal and perinatal death surveillance and response in Ethiopia: a systematic review.Reproductive health · 2025Pooled it
- 25 Years of Digital Health Toward Universal Health Coverage in Low- and Middle-Income Countries: Rapid Systematic Review.Journal of medical Internet research · 2025Pooled it
- Reducing outpatient wait times through telemedicine: a systematic review and quantitative analysis.BMJ open · 2025Pooled it
- Alarming findings of psycho-socio-spiritual interventions on physical, mental, and social health for children with cancer and their families in low- and middle-income countries: a meta-analysis.Frontiers in psychiatry · 2025Pooled it
- Effect of pharmacist care on clinical outcomes and therapy optimization in perioperative settings: A systematic review.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2024Pooled it
- Linking communities and health facilities to improve child health in low-resource settings: a systematic review.Health policy and planning · 2024Pooled it
- Effects of education on adult mortality: a global systematic review and meta-analysis.The Lancet. Public health · 2024Pooled it
- A multi-faceted hospital-based intervention for intrapartum care in sub-Saharan Africa: a stepped-wedge cluster-randomized trial.Nature medicine · 2026Trial
- Generative AI-enabled clinical decision support system in primary care: a pragmatic, cluster-randomized trial.Nature medicine · 2026Trial
- Quality of antenatal care provision in rural villages of Satna district, Madhya Pradesh, India: a quantitative formative study to help the development of an evidence-based contextualized complex health intervention of the CHAMPION2 cluster randomized trial.BMC pregnancy and childbirth · 2026Trial
- The impact of digital interventions on health insurance coverage for reproductive, maternal, newborn and child health services utilization in Kakamega, Kenya: a cluster randomized controlled trial.Health policy and planning · 2024Trial
- Health workers' perspectives on the quality of maternal and newborn health care around the time of childbirth: Results of the Improving MAternal Newborn carE in the EURO Region (IMAgiNE EURO) project in 12 countries of the World Health Organization European Region.Journal of global health · 2024Trial
- Effectiveness and Implementation of a Text Messaging mHealth Intervention to Prevent Childhood Obesity in Mexico in the COVID-19 Context: Mixed Methods Study.JMIR mHealth and uHealth · 2024Trial
- Unpacking the Role of Financial Incentives in the Motivation and Individual Performance of Nurses in LMICs: A Scoping Review Protocol.Public health challenges · 2026Review
- Improving paediatric quality of care through a Sweden-Uganda twinning partnership - reflections on implementation and early experiences from the child thrive project.Global health action · 2026Article
- Inpatient non-communicable disease patterns and influencing factors at two tertiary hospitals in New Zealand and China: a mixed-methods study protocol.Global health action · 2026Article
464 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUniversal health coverage has been proposed as a strategy to improve health in low-income and middle-income countries (LMICs). However, this is contingent on the provision of good-quality health care. We estimate the excess mortality for conditions targeted in the Sustainable Development Goals (SDG) that are amenable to health care and the portion of this excess mortality due to poor-quality care in 137 LMICs, in which excess mortality refers to deaths that could have been averted in settings with strong health systems.
methodsUsing data from the 2016 Global Burden of Disease study, we calculated mortality amenable to personal health care for 61 SDG conditions by comparing case fatality between each LMIC with corresponding numbers from 23 high-income reference countries with strong health systems. We used data on health-care utilisation from population surveys to separately estimate the portion of amenable mortality attributable to non-utilisation of health care versus that attributable to receipt of poor-quality care.
findings15·6 million excess deaths from 61 conditions occurred in LMICs in 2016. After excluding deaths that could be prevented through public health measures, 8·6 million excess deaths were amenable to health care of which 5·0 million were estimated to be due to receipt of poor-quality care and 3·6 million were due to non-utilisation of health care. Poor quality of health care was a major driver of excess mortality across conditions, from cardiovascular disease and injuries to neonatal and communicable disorders.
interpretationUniversal health coverage for SDG conditions could avert 8·6 million deaths per year but only if expansion of service coverage is accompanied by investments into high-quality health systems.
fundingBill & Melinda Gates Foundation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.