ReviewNeuroscience and biobehavioral reviews2018
Growing out of attention deficit hyperactivity disorder: Insights from the 'remitted' brain.
Review in Neuroscience and biobehavioral reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Combined family-based association and linkage analyses in families affected by attention-deficit hyperactivity disorder.Human genetics · 2026Pooled it
- The association between ADHD and physical health: a co-twin control study.Scientific reports · 2020Trial
- Developmental deviations of association-network structural connectivity in youths with ADHD predict symptom and treatment outcomes.Nature biomedical engineering · 2026Article
- ADHD symptom trajectories and brain morphometry: A longitudinal analysis.medRxiv : the preprint server for health sciences · 2026Article
- Developmental trajectories of glutamate and the variable clinical course of ADHD in youth.Translational psychiatry · 2026Article
- Adult ADHD in Cultural Ecosocial Niches: Exploring the Rise of Adult ADHD in Context.Culture, medicine and psychiatry · 2026Article
- Distinct neuroimaging subtypes of ADHD among adolescents based on semi-supervised learning.Translational psychiatry · 2025Article
- Cut from the same cloth: neurobiological continuity between childhood and adult ADHD.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- Epigenetic age across development in children and adolescents with ADHD.Psychiatry research · 2025Article
- Examining longitudinal associations between prenatal exposure to infections and child brain morphology.Brain, behavior, and immunity · 2024Article
- Cortico-striatal differences in the epigenome in attention-deficit/ hyperactivity disorder.Translational psychiatry · 2024Article
- Translating Decades of Neuroscience Research into Diagnostic and Treatment Biomarkers for ADHD.Advances in neurobiology · 2024Review
- Treatment biomarkers for ADHD: Taking stock and moving forward.Translational psychiatry · 2022Review
- Convergence mechanism of mindfulness intervention in treating attention deficit hyperactivity disorder: Clues from current evidence.World journal of clinical cases · 2022Review
- Associations of Air Pollution on the Brain in Children: A Brain Imaging Study.Research report (Health Effects Institute) · 2022Article
- Intrinsic Functional Connectivity in the Default Mode Network Differentiates the Combined and Inattentive Attention Deficit Hyperactivity Disorder Types.Frontiers in human neuroscience · 2022Article
- Compensatory mechanism of attention-deficit/hyperactivity disorder recovery in resting state alpha rhythms.Frontiers in computational neuroscience · 2022Article
- Structural brain morphometry as classifier and predictor of ADHD and reward-related comorbidities.Frontiers in psychiatry · 2022Article
- Associations between attention-deficit hyperactivity disorder (ADHD) symptom remission and white matter microstructure: A longitudinal analysis.JCPP advances · 2021Article
- Methylphenidate for attention-deficit/hyperactivity disorder in adults: a narrative review.Psychopharmacology · 2021Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
We consider developmental and cognitive models to explain why some children 'grow out' of attention deficit hyperactivity disorder (ADHD) by adulthood. The first model views remission as a convergence towards more typical brain function and structure. In support, some studies find that adult remitters are indistinguishable from those who were never affected in the neural substrates of 'top-down' mechanisms of cognitive control, some 'bottom-up' processes of vigilance/response preparation, prefrontal cortical morphology and intrinsic functional connectivity. A second model postulates that remission is driven by the recruitment of new brain systems that compensate for ADHD symptoms. It draws support from demonstrations of atypical, but possibly beneficial, patterns of connectivity within the cognitive control network in adult remitters. The final model holds that some childhood ADHD anomalies show lifelong persistence, regardless of adult outcome, supported by shared reports of anomalies in remitters and persisters in posterior cerebral and striato-thalamic regions. The models are compatible: different processes driving remission might occur in different brain regions. These models provide a framework for future studies which might inform novel treatments to 'accelerate' remission.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.