ArticleThe Laryngoscope2019
Association Between Age and Patient-Reported Changes in Voice and Swallowing After Thyroidectomy.
Article in The Laryngoscope, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Thyroidectomy-Related Dysphagia: A Systematic Literature Review.Medicina (Kaunas, Lithuania) · 2026Pooled it
- Swallowing disorders after thyroidectomy: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Pooled it
- Care and Management of Voice Change in Thyroid Surgery: Korean Society of Laryngology, Phoniatrics and Logopedics Clinical Practice Guideline.Clinical and experimental otorhinolaryngology · 2022Guideline
- Dysphagia following uncomplicated thyroidectomy: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019Pooled it
- Interaction Between Patient-Related and Surgical Factors in the Pattern of Voice Recovery Following Thyroidectomy: A Prospective Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- Long-Term Swallowing Outcomes Following Thyroidectomy: Clinical Determinants of Persistent Swallowing Symptoms in Endocrine Surgical Oncology Care.Healthcare (Basel, Switzerland) · 2026Article
- Voice changes following uncomplicated thyroid surgery: a prospective study in Iranian people.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Secondary analyses of swallowing efficiency and safety outcomes following thyroidectomy versus thyroidectomy plus prophylactic central neck dissection.Thyroid research · 2025Article
- SHAP-Based Identification of Potential Acoustic Biomarkers in Patients with Post-Thyroidectomy Voice Disorder.Diagnostics (Basel, Switzerland) · 2025Article
- Impact of Frailty on Post-Treatment Dysphagia in Patients with Head and Neck Cancer.Dysphagia · 2025Article
- Prospective Voice Assessment After Thyroidectomy Without Recurrent Laryngeal Nerve Injury.Diagnostics (Basel, Switzerland) · 2024Article
- Fluorescence imaging to visualize the recurrent laryngeal nerve during thyroidectomy procedures: analysis of 65 cases and 81 nerves.Surgical endoscopy · 2024Article
- Prevalence and risk factors for dysphagia in older adults after thyroid and parathyroid surgery.Surgery · 2024Article
- Results of Swallowing Assessment in the Immediate Postoperative Period in Patients Following Surgery for Thyroid Malignancies.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Voice and swallowing symptoms after thyroid surgery assessed using the ThyVoice online platform.European thyroid journal · 2023Article
- Post-thyroidectomy voice and swallowing disorders and association with laryngopharyngeal reflux: A scoping review.Laryngoscope investigative otolaryngology · 2023Article
- The Underreported Postoperative Suffering after Thyroid Surgery: Dysphagia, Dysphonia, and Neck Pain-A Cross-Sectional Study.Anesthesiology research and practice · 2023Article
- Nerve autofluorescence under near-ultraviolet light: cutting-edge technology for intra-operative neural tissue visualization in 17 patients.Surgical endoscopy · 2022Article
- Observational
- Evaluation of one-year incidence of vocal dysfunction and associated demographic factors in thyroidectomy patients: A descriptive analytical study.Annals of medicine and surgery (2012) · 2021Article
Corrections and comments
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Authors and funding
9 authors.
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Abstract
objectivesDespite intact recurrent laryngeal nerves, patient-reported voice and swallowing changes are common after thyroidectomy. The association between patient age or frailty status and these changes is unknown. The aim of this study was to evaluate the impact of age and frailty on the incidence of voice and swallowing alterations after thyroidectomy.
methodsWe performed an institutional review board (IRB)-approved retrospective review of consecutive patients who underwent total thyroidectomy with intraoperative recurrent laryngeal nerve (RLN) monitoring at a single institution between January 2014 and September 2016. Patients with RLN injury were excluded. After data extraction, a modified frailty index (mFI) was calculated for each patient. The association among risk factors, including age, mFI, prior history of neck surgery, frequent voice use, presence of malignancy or gastroesophageal reflux disease, and smoking status and reported voice and/or swallowing changes was examined.
resultsOf 924 patients undergoing thyroidectomy, 148 (16.0%) reported only changes in voice; 52 (5.6%) reported only difficulty in swallowing; and 26 (2.8%) reported changes with both voice and swallowing. On multivariate analysis, we found a significant increase in voice or swallowing alterations up to the age of 50 years (5% increased odds per year), after which these changes plateaued. We found that mFI was not associated with voice or swallowing changes.
conclusionAge ≥ 50 years is independently associated with the development of voice or swallowing changes after thyroidectomy, despite intact RLN. Additional prospective studies are needed to validate these findings, further define this association, and identify risk factors for developing these changes. LEVEL OF EVIDENCE: 2b Laryngoscope, 129:519-524, 2019.
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