Evidence map›Paper›PMID 30194622›Full record

ReviewPharmacoEconomics2019

Ribociclib with an Aromatase Inhibitor for Previously Untreated, HR-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.

Nasuh C Büyükkaramikli, Saskia de Groot, Rob Riemsma, Debra Fayter, Nigel Armstrong, Piet Portegijs, Steven Duffy, Jos Kleijnen, Maiwenn J Al

Registry-linked trialAbstract readReview
In one paragraph

Review in PharmacoEconomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05163106 (Presurgical Treatment With Ribociclib and Letrozole in Patients With Locally Advanced Breast Cancer), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05163106 phase2completednot on this mapstarted 2022, after this paper: background citation

Presurgical Treatment With Ribociclib and Letrozole in Patients With Locally Advanced Breast Cancer: the NEOLETRIB Study.

TypeinterventionalSponsorUniversity Hospital, AkershusRan2022 to 2024Enrolled85ConditionsBreast Cancer, HER2-negative Breast Cancer, ER-positive Breast Cancer, Locally Advanced Breast CancerArmsLetrozole 2.5mg oral tablet, Ribociclib 600mg oral tablet, Goserelin
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Cost-effectiveness of ribociclib plus letrozoleTherapeutic advances in medical oncology · 2021
    Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nasuh C BüyükkaramikliInstitute for Medical Technology Assessment (iMTA), Erasmus School of Health Policy & Management (ESHPM), Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands. buyukkaramikli@imta.eur.nl.ORCID 0000-0002-2021-9574
Saskia de GrootInstitute for Medical Technology Assessment (iMTA), Erasmus School of Health Policy & Management (ESHPM), Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands.
Rob RiemsmaKleijnen Systematic Reviews Ltd, York, UK.
Debra FayterKleijnen Systematic Reviews Ltd, York, UK.
Nigel ArmstrongKleijnen Systematic Reviews Ltd, York, UK.
Piet PortegijsDepartment of Family Medicine, School for Public Health and Primary Care (CAPHRI), Maastricht University, Maastricht, The Netherlands.
Steven DuffyKleijnen Systematic Reviews Ltd, York, UK.
Jos KleijnenKleijnen Systematic Reviews Ltd, York, UK.
Maiwenn J AlInstitute for Medical Technology Assessment (iMTA), Erasmus School of Health Policy & Management (ESHPM), Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands.

Funding

Department of Health 16/112/03 STA
6 · The paper itself

Abstract

The National Institute for Health and Care Excellence, as part of the institute's single technology appraisal process, invited the manufacturer of ribociclib (Kisqali

Indexed as

AminopyridinesAntineoplastic Combined Chemotherapy ProtocolsAromatase InhibitorsBreast NeoplasmsCost-Benefit AnalysisFemaleHumansModels, EconomicPurinesRandomized Controlled Trials as TopicReceptors, EstrogenTechnology Assessment, BiomedicalAminopyridinesAromatase InhibitorsPurinesReceptors, Estrogenribociclib

Identifiers

PMID30194622
PMCPMC6386053

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.