ArticleScientific reports2018
Construction of Self-defensive Antibacterial and Osteogenic AgNPs/Gentamicin Coatings with Chitosan as Nanovalves for Controlled release.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 34 citations in OpenAlex.
- Synergistic antibacterial and osteogenic properties of micro-arc oxidation GO@Ag/SF composite coatings for the repair of infectious bone defects.Bioactive materials · 2027Article
- Advanced surface engineering of titanium materials for biomedical applications: From static modification to dynamic responsive regulation.Bioactive materials · 2023Review
- Smart Bacteria-Responsive Drug Delivery Systems in Medical Implants.Journal of functional biomaterials · 2022Review
- A Review on Antibacterial Silk Fibroin-based Biomaterials: Current State and Prospects.Materials today. Chemistry · 2022Article
- Antibacterial Efficacies of Nanostructured Aminoglycosides.ACS omega · 2022Review
- Biomimetic Inorganic Nanoparticle-Loaded Silk Fibroin-Based Coating with Enhanced Antibacterial and Osteogenic Abilities.ACS omega · 2021Article
- Surface Engineering Strategies to Enhance the In Situ Performance of Medical Devices Including Atomic Scale Engineering.International journal of molecular sciences · 2021Review
- Small AgNP in the Biopolymer Nanocomposite System.International journal of molecular sciences · 2020Article
- Self-defensive antimicrobial biomaterial surfaces.Colloids and surfaces. B, Biointerfaces · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To solve the Ti implants-associated infection and poor osseointegration problems, we have constructed the AgNPs/gentamicin (Gen)-loaded silk fibroin (SF) coating with acceptable antibacterial and osteogenic aptitude. Nevertheless, due to uncontrollably sustained drug release, this bactericidal coating encountered some tricky problems, such as local high Ag concentration, short life-span and potential cytotoxicity. In this work, a chitosan (CS) barrier layer was constructed to prebuilt the SF-based film by two means, dip-coating (DCS) and spin-coating (SCS). Intriguingly, the CS barrier layer constructed by spin-coating highly improved the hydrophilic and protein-absorbed performances. As verified in the release profile, both coatings showed a prolonged and pH-dependent pattern of Ag
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.